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Ebselen

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Formula: C13H9NOSe
CAS: 60940-34-3
search Element: ebselen

Identification

Structural Formula
Ebselen
CAS:
60940-34-3
EINECS:
Molecular Formula:
C13H9NOSe
MDL:
MFCD00210937
SMILES:
C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2
Synonym:
ebselen 99% ; spi-1005 ; dr-3305 ; nsc 639762 ; pz51 ; ebselen ; harmokisane ; ebselen,99% ; ccg-39161 ; rp-60931


Description

Ebselen is an interesting organoselenium compound displaying antiinflammatory and antioxidant properties. Ebselen is shown to inhibit the 5-lipoxygenase (5-LO) and 15-lipoxygenase (15-LO) enzymes in the absence of glutathione. Ebselen also inhibits Cox (cyclooxygenase), PKC (protein kinase C), DECR1 (NADPH), and Mox-1 (NADPH oxidase). The oxidation of low density lipoproteins by free radicals is suppressed by the antioxidant action of Ebselen. Ebselen is an inhibitor of Cox-1, Cox-2, NOS, GST and IDO.


Suppliers

Ambeed, Inc.
A121080
Aea.ltd
A4998
Chemlyte Solutions
CS126378
A.G. Scientific
AS105315
CSNpharm, Inc.
CSN10885
Pharmacore Co., Limited
PL161483
AK Scientific, Inc.
AS133399
BOC Sciences
BS84252
Leap Chem Co., Ltd
LC126378
Santa Cruz Biotechnology, Inc.
200740
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Prices & Availability




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Properties for Ebselen

Molecular Weight:
274.18 g·mol−1
Melting point:
178-181 °C
Boiling point:
~402.8° C at 760 mmHg (Predicted)
Solubility:
Soluble in PBS pH7.2, DMSO (25 mg/ml), ethanol (10 mg/ml), methanol, acetone, acetonitrile, and DMF (~5 mg/ml).
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Safety & Transport Information

Risk Codes:
R23/25 - Toxic by inhalation and if swallowed
R33 - Danger of cumulative effects
R36/37/38 - Irritating to eyes, respiratory system and skin
R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Safety Codes:
S20/21 - When using do not eat, drink or smoke
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S28 - After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S60 - This material and its container must be disposed of as hazardous waste
S61 - Avoid release to the environment. Refer to special instructions/safety data sheet
Hazard Symbols:
T, N, Xi
Hazard symbol T Hazard symbol N Hazard symbol Xi
Storage temperature :
2-8°C
RID/ADR certification :
UN 3283 6.1 / PG 3
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Alternative Distributors of [Ebselen]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Hebei Oxen Special Chemicals Company Limited | Molekula GmbH | Nantong Chem-Tech. (Group) Co., Ltd. | Originchem Co., Ltd. | Anix-Chem Limited | Jinan Great Chemical Co., Ltd. | East Chemical Industry Co., Ltd. | BOC Sciences | Suzhou Vosun Chemical Co.,Ltd. | Gihi Chemicals Co., Limited

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MSDS:
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