Dutasteride | CAS 164656-23-9 | Chemical-Suppliers

Element: dutasteride

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C-S » Chemicals » dutasteride-PX71743

Identification

Dutasteride

CAS:

164656-23-9

EINECS:

Molecular Formula:

C₂₇H₃₀F₆N₂O₂

MDL:

MFCD00937869

SMILES:

C[C@]12CC[C@H]3[C@@H](CC[C@H]4NC(=O)C=C[C@]34C)[C@@H]1CC[C@@H]2C(=O)NC1=CC(=CC=C1C(F)(F)F)C(F)(F)F

Synonym:

dutasteride ; dutasteride(avodart) ; (5α,17β)- ; avolve ; duagen ; dutasteride (200 mg) ; gg-745, gi-198745, ; gi 198745 ; dutasteride api ; avodart

Description

Dutasteride is a 5-α-reductase inhibitor that inhibits the conversion of testosterone into dihydrotestosterone (DHT). Dutasteride inhibits both isoforms of 5-α reductase (5 α-Reductase 1/5aR1 and 5 α-Reductase 2/5aR2) to a similar extent (IC₅₀ 6nmol/l and 7 nmol/l, respectively), while finasteride only inhibits Type II. Dutasteride competed for binding the LNCaP cell AR with an IC₅₀ approximately 1.5 μM.

Suppliers

Ambeed, Inc.

A190042

Aozeal Certified Standards (AOCS), Inc.

D0022.12

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI7593036

Shandong Ench Chemical Co.,Ltd

SECC3301650

Shandong Minglang Chemical Co., Ltd

SMC3851540

H&Z Industry Co.,Ltd

HIC220880

Chemlyte Solutions

CS198594

Crystal Pharma (Gadea Grupo Farmacéutico)

CP4621848

Guangzhou Topwork Chemical Co., Ltd.

GTC3961584

Chemvon Biotechnology Co. Ltd.

CBC3301320

Shanghai Worldyang Chemical Co., Ltd.

SWC4071628

Xiamen Equation Chemical Co.,Ltd

XECC3521760

Sancai Industry Co.,Ltd.

SIC2641056

Hainan Zhongxin Chemical Co., Ltd.

HZC3741496

Aecochem Corp.

AC154462

Fox Chemicals GmbH

FC198594

CSNpharm, Inc.

CSN10879

Sigma-Aldrich International GmbH

SI3521056

Carbone Scientific Co., Ltd.

CS308924

AK Scientific, Inc.

AS209627

Xingrui Industry Co., Limited

XIL3191276

Leap Chem Co., Ltd

LC198594

Santa Cruz Biotechnology, Inc.

207600

Dayang Chem (Hangzhou) Co.,Ltd.

DC3411364

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Prices & Availability

Data is processed

Properties for Dutasteride

Molecular Weight:

528.53 g·mol−1

Density:

~1.3 g/cm³ (Predicted)

Melting point:

242-250 °C

Boiling point:

~620.3° C at 760 mmHg (Predicted)

Solubility:

Soluble in ethanol (44 mg/ml), methanol (64 mg/ml), polyethylene glycol 400 (3 mg/ml), and DMSO (62 mg/ml at 25° C 117mM). Insoluble in water.

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Storage temperature :

-20 °C Freezer

Alternative Distributors of [Dutasteride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified