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Doxifluridine

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Formula: C9H11FN2O5
CAS: 3094-09-5
search Element: doxifluridine
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Identification

Structural Formula
Doxifluridine
CAS:
3094-09-5
EINECS:
221-440-1
Molecular Formula:
C9H11FN2O5
MDL:
MFCD00866530
SMILES:
C[C@H]1O[C@H](C(O)[C@H]1O)N1C=C(F)C(=O)NC1=O
Synonym:
ro-21-9738 ; flutron ; 5-f-5‘-du ; furtulon ; 5'-dfur ; doxifluridine ; doxifluidine ; amc 0101 ; 5'dfurd ; 5-cl-5'-du


Description

Doxifluridine is a fluorinated pyrimidine nucleoside, which displays cytostatic activity. It is known that this compound is the inactive form of 5-Fluorouridine, which is converted by enzymes in vivo . Studies indicate that 5-Fluorouridine causes apoptosis in HCT-116 colorectal carcinoma cells and along with cDNA microarray is a useful tool in studying the expression of 1,200 genes during apoptosis. It is believed that 5-Fluorouridine induces cytotoxicity in cells not only by inhibition of RNA synthesis and processing, but through other unknown mechanisms as well. Doxifluridine is an activator of NF κ B in macrophages.


Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI8973588
+
XD BIOCHEMS Ltd
XB195585
+
Nantong Xindao Biotech Ltd
NXB3381352
+
Chemlyte Solutions
CS234702
+
Autech Industry Co.,Limited
AIC3511404
+
Ambeed, Inc.
A137458
+
Xinxiang Aurora Biotechnology Co., Ltd.
XAB5072028
+
ICC Chemical Corporation
ICC3121248
+
Xiamen Equation Chemical Co.,Ltd
XECC4162080
+
Sancai Industry Co.,Ltd.
SIC3121248
+
CSNpharm, Inc.
CSN10057
Hangzhou Lingrui Chemical Co., Ltd.
HLC4551820
+
Acinopeptide Co., Ltd.
A286572
AK Scientific, Inc.
AS247741
+
Amadis Chemical Company Limited
ACCL4032015
+
Leap Chem Co., Ltd
LC234702
+
Santa Cruz Biotechnology, Inc.
211379
Dayang Chem (Hangzhou) Co.,Ltd.
DC4031612
+
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Prices & Availability




Data is processed


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Properties for Doxifluridine

Molecular Weight:
246.19 g·mol−1
Density:
~1.6 g/cm3 (Predicted)
Melting point:
188-192 °C(lit.)
Solubility:
Soluble in water (50 mg/ml), DMSO (49 mg/ml at 25° C), ethanol (<1 mg/ml at 25° C), and methanol.
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Safety & Transport Information

Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Classes:
irritant, irritant-harmful
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
-20 °C Freezer
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Alternative Distributors of [Doxifluridine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Hebei Oxen Special Chemicals Company Limited | Inter-Chemical Ltd. | Farmachem SA Machineries & Marketing | Anhui Langxi Lianke Industrial Co., Ltd., | Hangzhou Onicon Chemical Co., Ltd. | 3B Scientific Corporation | Nanjing King-Pharm Co., Ltd. | Nantong Chem-Tech. (Group) Co., Ltd. | Jiangsu Honghui Pharmaceutical Co., Ltd. | Changzhou Sinly Pharmchem Co., Ltd. | Zibo Xinglu Chemical Industry Co., Ltd. | New Dragon Industrial Co., Ltd | Carbone Scientific Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Modachem Shanghai Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Hangzhou Pharma & Chem Co. Ltd. | Lanospharma Laboratories Co., Ltd. | TCS INDUSTRY LTD. | Jinan Great Chemical Co., Ltd. | Tocopharm Co., Ltd. | Mengjiangnan Chemical Co., Ltd | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Discovery Fine Chemicals Limited | King Tang Chemical Group Industry Co., Ltd. | Watson International Ltd | Shanghai Arbor Chemical Co., Ltd. | Wolves R&D Chemicals | Jinan Haohua Industry Co., Ltd. | Sino Rarechem Labs Co. Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Changzhou Union Chemicals Co.,Ltd. | Gihi Chemicals Co., Limited

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