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Donepezil hydrochloride

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Formula: C24H29NO3.HCl
CAS: 120011-70-3
search Element: hydrochloride donepezil
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Identification

Structural Formula
Donepezil hydrochloride
CAS:
120011-70-3
EINECS:
Molecular Formula:
C24H29NO3.HCl
MDL:
MFCD00881312
SMILES:
COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC.Cl
Synonym:
aricept ; bnag ; donepezil (aricept) ; donepezi ; akos 226-31 ; donepezil hydrochloride ; donepezil hcl ; aricept, e-2020 ; e-2020 ; e2020(pharmaceutical)


Description

Donepezil Hydrochloride is a noncompetitive acetylcholinesterase inhibitor (IC50 = 11.6 nM. It is known that Donepezil Hydrochloride is a useful tool in the study of Alzheimer's disease. Studies indicate that Donepezil Hydrochloride protects the brain against diisopropylfluorophosphate-induced effects. Studies indicate that Donepezil Hydrochloride selectively inhibits acetylcholinesterase, whereas it has little effect on butyrylcholinesterase. Alternate studies suggest that Donepezil Hydrochloride increases the concentration of extracellular acetylcholine.


Suppliers

Aea.ltd
A322644
+
Shandong SanYoung Industry Co., Ltd
SSI16106440
+
Ambeed, Inc.
A356134
+
Chemlyte Solutions
CS8282484
+
Aozeal Certified Standards (AOCS), Inc.
D0004.00
+
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI317412696
+
Shandong Ench Chemical Co.,Ltd
SECC13806900
+
H&Z Industry Co.,Ltd
HIC9203680
+
Chenghui Pharmaceutical Group Zone
CPGZ15647820
+
Xiamen Equation Chemical Co.,Ltd
XECC14727360
+
Carbone Scientific Co., Ltd.
CS12883864
+
AK Scientific, Inc.
AS8742622
+
Simagchem Corporation
SC9662898
+
Xingrui Industry Co., Limited
XIL13345336
+
BOC Sciences
BS5521656
+
Amadis Chemical Company Limited
ACCL14267130
+
Santa Cruz Biotechnology, Inc.
218265
Dayang Chem (Hangzhou) Co.,Ltd.
DC14265704
+
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CSNpharm, Inc.
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Santa Cruz Biotechnology, Inc.
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BLD Pharmatech Ltd
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Prices & Availability




Data is processed


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Properties for Donepezil hydrochloride

Molecular Weight:
415.95 g·mol−1
Melting point:
220-222 °C
Solubility:
Soluble in water (100 mM), DMSO (1 mg/ml), methanol, ethanol (2 mg/ml), and DMF (slightly).
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Safety & Transport Information

Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
-20 °C Freezer
RID/ADR certification :
UN 2811
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Alternative Distributors of [Donepezil hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Hebei Oxen Special Chemicals Company Limited | Inter-Chemical Ltd. | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Molekula GmbH | Ningbo Yuanfang Biochemicals Co., Ltd. | HuaiBei SanHe Developing Co., Ltd. | Hallochem Pharma Co., Ltd. | 3B Scientific Corporation | Afine Chemicals Limited | Xiang Ding Chemical International Co., Ltd | Nantong Chem-Tech. (Group) Co., Ltd. | Jinan Jinao Chemical Development Co., Ltd. | Jiangsu Honghui Pharmaceutical Co., Ltd. | Hefei Photochem Trading Co., Ltd | New Dragon Industrial Co., Ltd | Jinan Victory Imp. & Exp. Co., Ltd. | ShangHai Biochempartner Co., Ltd. | Discovery Fine Chemicals Limited | Formax Chemicals Co., Ltd. | Long Island Pharmaceutical & Chemical Co. Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai AOKChem Group Limited | Shanghai Kairen Industrial Co.,Ltd. | Jinan Dexinjia Bio&Tech Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Atomole Scientific Co., Ltd. | Lanospharma Laboratories Co., Ltd. | Suchem Pharma Co., Ltd. | TCS INDUSTRY LTD. | Nantong Qihai Chemicals Co., Ltd. | AOKBIO Co., Ltd. | ForeChem Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Jinan Great Chemical Co., Ltd. | ZhangJiaGang CAE International Trading Co., Ltd. | East Chemical Industry Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Greenlife Biotechnology Co.,Ltd. | Watson International Ltd | Changzhou Weijia Chemical Co.,Ltd. -WJCHEM- | BOC Sciences | Hubei Yuancheng Saichuang Tech.Co.,Ltd | Sciyu Biotech Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Clearsynth Canada INC. | Green Fine Chemical (Shanghai) Co., Ltd. | Wanko Chemical Co., Ltd.

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