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Docosahexaenoyl Ethanolamide

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Formula: C24H37NO2
CAS: 162758-94-3

Identification

Structural Formula
Docosahexaenoyl Ethanolamide
CAS:
162758-94-3
EINECS:
Molecular Formula:
C24H37NO2
MDL:
MFCD12912674
SMILES:
CC/C=CC/C=CC/C=CC/C=CC/C=CC/C=CCCC(=O)NCCO
Synonym:
synaptamide ; n-docosahexaenoylethanolamide ; dehydroepiandrosteron(dhea) ; (4z,7z,10z,13z,16z,19z)-n-(2-hydroxyethyl)docosa-4,7,10,13,16,19-hexaenamide ; n-(2-hydroxyethyl)-4z,7z,10z,13z,16z,19z-docosahexaenamide ; docosahexaenoyl ethanolamide


Description

Docosahexaenoyl Ethanolamide (DHEA) is an ethanolamine amide of DHA that has been detected in both retina and brain at concentrations similar to those for arachidonoyl ethanolamide (AEA). Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, particularly in the retina and brain. A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets on a DHA-supplemented diet compared to a DHA-free control diet. DHEA binds rat brain CB1 receptor with a Ki of 324 nM, which is about 10-fold higher than the Ki for AEA. DHEA inhibits shaker-related voltage-gated potassium channels in the brain slightly better than AEA, with an IC50 of 1.5 μM.


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Santa Cruz Biotechnology, Inc.
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Dayang Chem (Hangzhou) Co.,Ltd.
DC17366944
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Synaptamide
Salsbury Chemicals, Inc.
SC264792

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Properties for Docosahexaenoyl Ethanolamide

Molecular Weight:
371.561 g·mol−1
Boiling point:
78° C
Solubility:
Soluble in ethanol, DMSO (~20 mg/ml), DMF (~20 mg/ml), PBS (pH 7.2) (~0.15 mg/ml), and water (0.15 mg/ml at 25° C).
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Safety & Transport Information

Storage temperature :
?20 °C
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Alternative Distributors of [Docosahexaenoyl Ethanolamide]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

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MSDS:
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