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17-DMAG

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Formula: C32H48N4O8.HCl
CAS: 467214-21-7
search Element: dmag
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Identification

Structural Formula
17-DMAG
CAS:
467214-21-7
EINECS:
Molecular Formula:
C32H48N4O8.HCl
MDL:
SMILES:
CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCCN(C)C)C)OC)OC(=O)N)C)C)O)OC
Synonym:


Description

17-DMAG, 17-dimethylaminoethylamino-17-demethoxygeldanamycin, is a synthetic derivative of the antibiotic Geldanamycin with lower hepatotoxicity than the parent antibiotic and higher potency and availability than the similar derivative 17-AAG. 17-DMAG is described to bind and inhibit the activity of Hsp90 (heat shock protein 90), a cellular chaperone that is over expressed in many cancers, and which participates in folding of proteins found in multiple signal transduction pathways.


Suppliers

Santa Cruz Biotechnology, Inc.
202005
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Chemlyte Solutions
CS90000270000

Prices & Availability




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Properties for 17-DMAG

Solubility:
Soluble in water, ethanol (10 mg/mL), and DMSO (>25 mg/mL).
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Safety & Transport Information

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Alternative Distributors of [17-DMAG]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

ShangHai Biochempartner Co., Ltd.

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