Diphenhydramine hydrochloride | CAS 147-24-0

Element: diphenhydramine hydrochloride

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Identification Properties Suppliers Prices & Availability Get Quick Quote

C-S » Chemicals » diphenhydramine-hydrochloride-PX67423

Identification

Diphenhydramine hydrochloride

CAS:

147-24-0

EINECS:

205-687-2

Molecular Formula:

C₁₇H₂₁NO.HCl

MDL:

MFCD00012479

SMILES:

CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl

Synonym:

bax ; contac ; felben ; resmin ; bcl2l4 ; ambenyl ; actifed ; benylin ; prodryl ; rohydra

Description

Diphenhydramine hydrochloride blocks the effect of histamine at Histamine H1 Receptor (H1 receptor) sites, which results in an increase in vascular smooth muscle contraction. Diphenhydramine hydrochloride has been shown to have inhibitive tumor promotion properties. The compound decreases peripheral nociceptors sensitization. Diphenhydramine hydrochloride was found to inhibit re-uptake of the neurotransmitter serotonin, which led to a search for viable antidepressants with similar structures and fewer side effects, such as selective serotonin re-uptake inhibitor (SSRI). Diphenhydramine hydrochloride also acts as a sodium channel blocker, which is responsible for its actions as a local anesthetic. The labeled form of this product is also available, Diphenhydramine-d6 Hydrochloride. Diphenhydramine hydrochloride is an inhibitor of mAChR M1.

Suppliers

Shandong SanYoung Industry Co., Ltd

SSI20308120

Chemlyte Solutions

CS10443132

Aozeal Certified Standards (AOCS), Inc.

D0040.00

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI400216008

H&Z Industry Co.,Ltd

HIC11604640

Autech Industry Co.,Limited

AIC15666264

Krada CPS Industry S.L

KCIS12766380

Vivimed Labs USA Inc

VLUI11605800

Recordati S.P.A.

RS9282784

H. Interdonati, Inc.

HI11603480

CAF International Corp.

CIC13345336

RFI Ingredients

RI8702610

B.M.P. Bulk Medicines & Pharmaceuticals GmbH

BBMP255212760

CellMark AB

CA6381914

AXO Industry SA

AIS8703480

Caesar & Loretz GmbH

CL11603480

Xiamen Equation Chemical Co.,Ltd

XECC18569280

Sancai Industry Co.,Ltd.

SIC13925568

Hainan Zhongxin Chemical Co., Ltd.

HZC19727888

Aecochem Corp.

AC8122436

Sigma-Aldrich International GmbH

SI18565568

Xingrui Industry Co., Limited

XIL16826728

Leap Chem Co., Ltd

LC10443132

Santa Cruz Biotechnology, Inc.

204729

Dayang Chem (Hangzhou) Co.,Ltd.

DC17987192

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CAS equal suppliers

Diphenhydramine HCl

CSNpharm, Inc.

CSN16168

Diphenhydramine HCL USP

CellMark AB

CA7592277

Benzhydramine hydrochloride

AK Scientific, Inc.

AS10263078

Diphenhydramine-d6 Hydrochloride

Santa Cruz Biotechnology, Inc.

sc-218244

Diphenhydramine hydrochloride, 99%

Alfa (A Johnson Matthey Company)

A21766528

Diphenhydramine hydrochloride, 99%

Acros Organics BVBA

AOB12925168

Diphenhydramine hydrochloride, Pharma

Zeta Pharmaceuticals Inc.

ZP27758325

Diphenhydramine hydrochloride, Pharma

IBIS Chemie International

ICI277511100

2-(Benzhydryloxy)-N,N-dimethylethanamine hydrochloride

BLD Pharmatech Ltd

BP486014580

N-(2-Diphenylmethoxyethyl)-N,N-dimethylamine hydrochloride

Finetech Industry Limited

FIL725029000

Ethanamine, 2-(diphenylmethoxy)-n,n-dimethyl-, hydrochloride

Angene International Limited

AGN-PC-071M56

Ethanamine,2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride (1:1)

Gihi Chemicals Co., Limited

GCL1053042120

Prices & Availability

Data is processed

Properties for Diphenhydramine hydrochloride

Molecular Weight:

291.82 g·mol−1

Density:

1.2 g/cm³

Melting point:

168-172 °C

Solubility:

Soluble in water (1000 mg/ml), DMSO (58 mg/ml at 25° C), DMF (~10 mg/ml), methanol, and ethanol (500 mg/ml).

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R22 - Harmful if swallowed
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S7 - Keep container tightly closed

Hazard Symbols:

Xn, T, F

Storage temperature :

Desiccate at RT

RID/ADR certification :

2811

Alternative Distributors of [Diphenhydramine hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

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MSDS:

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