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1,4-Dioxane

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Formula: C4H8O2
CAS: 123-91-1
search Element: dioxane

Identification

Structural Formula
1,4-Dioxane
CAS:
123-91-1
EINECS:
204-661-8
Molecular Formula:
C4H8O2
MDL:
MFCD00006571
SMILES:
C1COCCO1
Synonym:
dioxanne ; arose ief ; dioxan-1,4 ; diokan ; p-dioxane ; p-dioxan ; aaaaa ; dioksan ; diox ; dioxan


Description

1,4-Dioxane is a hetorocyclic organic compound and aprotic solvent that has been used on lysozymes to observe conformational effects. The compound can sometimes act as a substitute for Tetrahydrofuran due to its lower toxicity.


Suppliers

H&Z Industry Co.,Ltd
HIC220880
Autech Industry Co.,Limited
AIC2971188
Krada CPS Industry S.L
KCIS2421210
Shandong SanYoung Industry Co., Ltd
SSI3851540
Create Chemical Co., Ltd.
CC275825
Chemlyte Solutions
CS198594
Shandong Ench Chemical Co.,Ltd
SECC3301650
Lori Industry Co., Ltd
LI242726
Brand-Nu Laboratories, Inc.
BL297891
Hangzhou Cherry Pharmaceutical Technology Co., Ltd.
HCPT5612805
Austin Chemical Company, Inc.
ACC3191276
INNOCHEM
I88176
CellMark AB
CA121363
Shanghai Yayu Biomedical Co., Ltd
SYB3631452
Sancai Industry Co.,Ltd.
SIC2641056
Hainan Zhongxin Chemical Co., Ltd.
HZC3741496
Daming Changda Co., Ltd.
DC264792
Aecochem Corp.
AC154462
Hangzhou Keying Chem Co., Ltd.
HKC3301320
Hangzhou Lingrui Chemical Co., Ltd.
HLC3851540
Sigma-Aldrich International GmbH
SI3521056
CM Fine Chemicals
CFC187748
Xingrui Industry Co., Limited
XIL3191276
Zehao Industry Co., Ltd.
ZI264792
Leap Chem Co., Ltd
LC198594
Santa Cruz Biotechnology, Inc.
208794
Dayang Chem (Hangzhou) Co.,Ltd.
DC3411364
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Aozeal Certified Standards (AOCS), Inc.
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CellMark AB
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Haihang Industry Co., Ltd.
HI4421326
1,4-Dioxacyclohexane
ShangHai Biochempartner Co., Ltd.
BCP16201
1,4-Dioxacyclohexane
Excenen Pharmatech Co., Ltd.
EN-1275
1,4-Dioxane, unstab.
Biosolve B.V.
BB5602240
Dioxane for pesticide analyses
scienTEST - bioKEMIX GmbH
S-B300012000
1,4-Dioxane (stabilized with BHT)
TCI Chemicals (India) Pvt. Ltd.
D0860
1,4-Dioxane, 99%, Extra Dry, anhydrous, AcroSeal
Acros Organics BVBA
AOB456018240
1,4-Dioxane, 99.8%, Extra Dry, stabilized, AcroSeal
Acros Organics BVBA
AOB484519380
1,4-Dioxane (1mg/mL in Methanol) [for Water Analysis]
TCI Chemicals (India) Pvt. Ltd.
S0619
1,4-Dioxane, 99.5%, Extra Dry over Molecular Sieve, AcroSeal
Acros Organics BVBA
AOB798031920

Prices & Availability




Data is processed


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Properties for 1,4-Dioxane

Molecular Weight:
88.10512 g·mol−1
Density:
1.034 g/mL at 25 °C(lit.)
Melting point:
12 °C
Boiling point:
101 °C
Flash point:
54 ºF
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Hazard Statements

GHS02

GHS02
Flammable
  • Flammable gases, category 1
  • Flammable aerosols, categories 1, 2
  • Flammable liquids, categories 1, 2, 3
  • Flammable solids, categories 1, 2
  • Self-reactive substances and mixtures, types B, C, D, E, F
  • Pyrophoric liquids, category 1
  • Pyrophoric solids, category 1
  • Combustible solids, category 3
  • Combustible liquids, category 3
  • Self-heating substances and mixtures, categories 1, 2
  • Substances and mixtures, which in contact with water, emit flammable gases, categories 1, 2, 3
  • Organic peroxides, types B, C, D, E, F
GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization
GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:
R10 - Flammable
R11 - Highly flammable
R19 - May form explosive peroxides
R22 - Harmful if swallowed
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R36/37 - Irritating to eyes and respiratory system
R36/37/38 - Irritating to eyes, respiratory system and skin
R36/38 - Irritating to eyes and skin
R37/38 - Irritating to respiratory system and skin
R38 - Irritating to skin
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
R40 - Limited evidence of a carcinogenic effect
R41 - Risk of serious damage to eyes
R45 - May cause cancer
R46 - May cause inheritable genetic damage
R48/20/22 - Harmful: danger of serious damage to health by prolonged exposure through inhalation and if swallowed
R48/23/24/25 - Toxic: danger of serious damage to health by prolonged exposure through inhalation, in contact with skin and if swallowed
R65 - Harmful: may cause lung damage if swallowed
R66 - Repeated exposure may cause skin dryness or cracking
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S23 - Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer)
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S46 - If swallowed, seek medical advice immediately and show this container or label
S53 - Avoid exposure - obtain special instructions before use
S62 - If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label where possible
S7 - Keep container tightly closed
S9 - Keep container in a well-ventilated place
Hazard Classes:
3
Hazard Symbols:
Xn, F, T
Hazard symbol T Hazard symbol F Hazard symbol Xn
Storage temperature :
Flammables area
RID/ADR certification :
UN 1993 3 / PG 2
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Alternative Distributors of [1,4-Dioxane]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

DKSH International AG | BOC Sciences | ABCR GmbH & Co. KG | Tedia Company, Inc. | Pfaltz & Bauer, Inc. | Hefei Photochem Trading Co., Ltd | Jinan Great Chemical Co., Ltd. | Lanospharma Laboratories Co., Ltd. | Xiang Ding Chemical International Co., Ltd | Watson International Ltd | Scandinavian Formulas, Inc. | Ruiyi Medical Co., Ltd. | Jiangsu Senxuan Pharmaceutical and Chemical Co.,Ltd. | TCI Europe NV | Chem-Impex International, Inc. | Yongyi Chemicals Group Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Ningbo Pangs Chem Int'l Co., Ltd. | Carl Roth GmbH + Co KG | Suzhou Rovathin Pharmatech Co., Ltd | Bichem Lab Co., Ltd. | Shanghai Marketing Center of Yangzhou Princechem Co., Ltd. | 3Way Pharm Inc. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd.

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