1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine | CAS 4004-05-1

Element: phosphoethanolamine dioleoyl glycero

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C-S » Chemicals » dioleoyl-glycero-phosphoethanolamine-PX67064

Identification

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine

CAS:

4004-05-1

EINECS:

Molecular Formula:

C₄₁H₇₈NO₈P

MDL:

MFCD00057986

SMILES:

CCCCCCCCC=C/CCCCCCCC(=O)OC[C@H](COP(O)(=O)OCCN)OC(=O)CCCCCCCC=C/CCCCCCCC

Synonym:

18:1 pe ; l-a-phosphatidylethanolamine dioleoyl ; dioleoylphosphatidylethanolamine ; 1,2-dioleoyl-sn-glycero-3-phosphorylethanolamine ; dioleoyl phosphoethanolamine ; ethanol, 2-amino-,dihydrogen phosphate (ester), monoester with 1,2-diolein, l- (8ci) ; 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine ; 9-octadecenoic acid(9z)-,1,1'-[(1r)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl]ester ; pe(18:1(9z)/18:1(9z)) ; l-beta,gamma-dioleoyl-alpha-cephalin ; 9-octadecenoicacid (9z)-, (1r)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediylester (9ci) ; 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine ; l-?,?-dioleoyl-?-cephalin ; 9-octadecenoic acid (z)-,1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester, (r)- ; dioleoyl phosphatidyl ethanolamine ; dioleoyl-l-a-phosphatidylethanolamine ; olein, 1,2-di-, 2-aminoethyl hydrogen phosphate, l- (8ci) ; coatsome me-8181 (dope) ; coatsome mc 8181 ; 1,2-dioleoyl-sn-glycero-3-pe ; dope ; coatsome me8181

Description

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) is a phospholipid emulsifier that has been used for improved DNA-liposome complex transport across membranes. Commonly used with the cationic emulsifier DOTAP ( 3-trimethylammonium-propane)(sc-202589), DOPE reduces the toxic effects of DOTAP alone and has been shown to have a high DNA trapping efficiency of 89% at a DOTAP:DOPE ratio of 2:1 in emulsions. The compound is ideal for use in gene transfer studies for both conditions with serum, in vivo, and without.

Suppliers

Autech Industry Co.,Limited

AIC24309720

Lori Industry Co., Ltd

LI19805940

Create Chemical Co., Ltd.

CC22506750

Santa Cruz Biotechnology, Inc.

202002

Dayang Chem (Hangzhou) Co.,Ltd.

DC279011160

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CAS equal suppliers

DOPE

BOC Sciences

BS48144

Dioleoyl phosphoethanolamine

Chemieliva Pharmaceutical Co., Ltd.

CP19605880

Dioleoyl phosphoethanolamine

Leap Chem Co., Ltd

LC10083024

Dioleoyl phosphoethanolamine

Finipharma Ltd

F7841568

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, fluorescein-labeled

Santa Cruz Biotechnology, Inc.

sc-297912

(Z)-(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dioleate

BLD Pharmatech Ltd

BP1663249896

Prices & Availability

Data is processed

Properties for 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine

Molecular Weight:

744.03 g·mol−1

Density:

1.008 g/cm3

Boiling point:

759.2 °C at 760 mmHg

Flash point:

413 °C

Solubility:

Soluble in water (partly), chloroform, methanol, 100% ethanol, 2-propanol, tetrahydrofurane, methylene chloride, and CHCl3:MeOH (9:1) (25 mg/ml).

Physical Description:

lyophilized powder

Safety & Transport Information

Risk Codes:

R20 - Harmful by inhalation
R22 - Harmful if swallowed
R36/38 - Irritating to eyes and skin
R38 - Irritating to skin
R40 - Limited evidence of a carcinogenic effect
R48/20/22 - Harmful: danger of serious damage to health by prolonged exposure through inhalation and if swallowed
R63 - Possible risk of harm to the unborn child
R67 - Vapours may cause drowsiness and dizziness

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves

Hazard Symbols:

Storage temperature :

-20°C

RID/ADR certification :

UN 1888 6.1 / PG 3

Alternative Distributors of [1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Jinan Great Chemical Co., Ltd.

Downloads

Mol File:

-/-

MSDS:

-/-

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