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2,3-dinor-8-iso Prostaglandin F2α

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Formula: C18H30 O5
CAS: 221664-05-7

Identification

Structural Formula
2,3-dinor-8-iso Prostaglandin F2α
CAS:
221664-05-7
EINECS:
Molecular Formula:
C18H30 O5
MDL:
SMILES:
CCCCCC(C=CC1C(CC(C1CC=CCC(=O)O)O)O)O
Synonym:
2,3-dinor ipf2a-iii ; 9alpha,11alpha-15s-trihydroxy-2,3-dinor-(8beta)-prosta-5z, 13e-dien-1-oic acid ; 2,3-dinor-8-isopgf2a ; 2,3-di-nor-8-isoprostaglandin f2a ; 3-pentenoic acid,5-[(1s,2r,3r,5s)-3,5-dihydroxy-2-[(1e,3s)-3-hydroxy-1-octen-1-yl]cyclopentyl]-,(3z)- ; prostaglandine ; 3-pentenoicacid, 5-[(1s,2r,3r,5s)-3,5-dihydroxy-2-[(1e,3s)-3-hydroxy-1-octenyl]cyclopentyl]-,(3z)- (9ci) ; 2,3-dinor-ipf2alpha-iii ; 2,3-dinor-8-iso prostaglandin f2alpha ; 2,3-di-nor-8-isoprostaglandin f2α ; 2,3-dinor-8-iso prostaglandin f1a


Description

2,3-dinor-8-iso Prostaglandin F2α is an F2 isoprostane metabolite, that has been shown to be produced in vivo by free radical-dependent peroxidation of Arachidonic Acid. It has been observed that the concentration of 2,3-dinor-8-iso Prostaglandin F2α increases in situations of oxidative stress. This non-enzymatic production of prostaglandins is thought to limit the efficacy of COX-2 inhibitors, and could potentially be used as a measurement of oxidative stress.


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2,3-dinor-8-iso Prostaglandin F2alpha
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Properties for 2,3-dinor-8-iso Prostaglandin F2α

Molecular Weight:
326.43 g·mol−1
Density:
1.189 g/cm3
Boiling point:
511.5°C at 760 mmHg
Flash point:
277.2°C
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Safety & Transport Information

Risk Codes:
R11 - Highly flammable
R36 - Irritating to eyes
R66 - Repeated exposure may cause skin dryness or cracking
R67 - Vapours may cause drowsiness and dizziness
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S29 - Do not empty into drains
S33 - Take precautionary measures against static discharges
Hazard Symbols:
F, Xi
Hazard symbol F Hazard symbol Xi
Storage temperature :
-20°C
RID/ADR certification :
UN 1231 3 / PG 2
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MSDS:
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