Dimethyloxaloylglycine (DMOG) | CAS 89464-63-1

Element: dimethyloxaloylglycine dmog

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C-S » Chemicals » dimethyloxaloylglycine-dmog-PX78209

Identification

Dimethyloxaloylglycine (DMOG)

CAS:

89464-63-1

EINECS:

Molecular Formula:

C₆H₉NO₅

MDL:

MFCD05865098

SMILES:

COC(=O)CNC(=O)C(=O)OC

Synonym:

dmog dimethyloxalylglycine n-[(methoxycarbonyl)methyl]oxamic acid methyl ester ; dmog, >=98% ; n-(2-methoxy-2-oxoacetyl)glycine methyl ester ; n-[(methoxycarbonyl)methyl]oxamic acid methyl ester ; dimethyloxaloylglycine ; n-(methoxyoxoacetyl)-glycine methyl ester ; dimethyloxallyl glycine ; dimethyloxalylglycine ; dmog ; dimethyloxaloylglycine (dmog)

Description

Dimethyloxaloylglycine (DMOG) is an inhibitor of prolyl hydroxylase (PHD) and the asparaginyl hydroxylase factor inhibiting HIF (FIH). DMOG has been observed to upregulate hypoxia inducible factor-1α (HIF-1α) in HMEC-1 cells, attenuating redox factor 1 (REF-1). PHT cells exposed to DMOG were observed to upregulate the follistatin-like 3 (FSTL3) transcription. Attenuation of myocardial injury by DMOG was also demonstrated using a rabbit ischemia reperfusion model. In NGF deprived neurons, DMOG increased cell survival through inhibition of cytochrome c release.

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Prices & Availability

Data is processed

Properties for Dimethyloxaloylglycine (DMOG)

Molecular Weight:

175.14 g·mol−1

Density:

1.25 g/cm³ (Predicted)

Melting point:

46-48°C

Safety & Transport Information

Risk Codes:

R22 - Harmful if swallowed

Hazard Classes:

irritant

Hazard Symbols:

Xi, Xn

Storage temperature :

Refrigerator

Alternative Distributors of [Dimethyloxaloylglycine (DMOG)]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Hebei Oxen Special Chemicals Company Limited | Matrix Scientific

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