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(S)-10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride

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Formula: C23H23N3O5.HCl
CAS: 119413-54-6
search Element: dimethylamino hydrochloride indolizino dihydroxy quinoline methyl pyrano dione ethyl
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Identification

Structural Formula
(S)-10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride
CAS:
119413-54-6
EINECS:
Molecular Formula:
C23H23N3O5.HCl
MDL:
MFCD00866235
Synonym:
hydrochloride ; skfs 104864a ; skf-104864a ; levulan-13c ; topotecan hcl ; 5-ala hcl-13c ; skf-s 104864-a ; nogitecan hcl ; nsc 609669 ; hycamtin




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1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-monohydrochloride, (4S)-
BLD Pharmatech Ltd
BP40320120960

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Properties for (S)-10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride

Molecular Weight:
457.91 g·mol−1
Melting point:
213-218 °C
Boiling point:
782.9° C at 760 mmHg (Predicted)
Solubility:
Soluble in methanol, water (92 mg/ml at 25° C), DMSO (92 mg/ml at 25° C), ethanol (<1 mg/ml at 25° C), and 1: 1 solution of DMSO: PBS (pH 7.2, ~0.5 mg/ml).
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Hazard Statements

GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:
R25 - Toxic if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R46 - May cause inheritable genetic damage
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
T
Hazard symbol T
Storage temperature :
Refrigerator
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Alternative Distributors of [(S)-10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Unispec Chemicals Co. | Molekula GmbH | Suzhou Highfine Biotech Co.,Ltd. | 3B Scientific Corporation | Shanghai Eagle Chemical Co., Ltd. | Afine Chemicals Limited | Xiang Ding Chemical International Co., Ltd | Nantong Chem-Tech. (Group) Co., Ltd. | Jiangsu Honghui Pharmaceutical Co., Ltd. | Pharmasi Chemicals Co., Ltd. | Melone Pharmaceutical Co., Ltd. | New Dragon Industrial Co., Ltd | Zhejiang Esun Chemical Co., Ltd. | Shanghai Tauto Biotech Co., Ltd. | Hubei Honch Pharmaceutical Co., Ltd. | Hangzhou Hysen Pharma Co., Ltd. | Genatal Life Science Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai Yingxuan Chempharm Co., Ltd. | Shanghai AOKChem Group Limited | Share Chemical Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Ark Pharm, Inc. | Sanowart Group Co., Ltd. | Bepharm Ltd. | Lanospharma Laboratories Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Jinan Great Chemical Co., Ltd. | Bichem Lab Co., Ltd. | East Chemical Industry Co., Ltd. | API Vanguard | Cfm Oskar Tropitzsch GmbH | Yongyi Chemicals Group Co., Ltd. | Pharmfar Co., Ltd. | Watson International Ltd | Greenlife Biotechnology Co.,Ltd. | BOC Sciences | Taizhou Creating Chemical Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Wanko Chemical Co., Ltd. | Haihang Industry Co., Ltd. | Clearsynth Canada INC.

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