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Dimebolin dihydrochloride

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Formula: C21H25N3
CAS: 3613-73-8

Identification

Structural Formula
Dimebolin dihydrochloride
CAS:
3613-73-8
EINECS:
Molecular Formula:
C21H25N3
MDL:
MFCD00387540
SMILES:
CC1=CC2=C(C=C1)N(C3=C2CN(CC3)C)CCC4=CN=C(C=C4)C.Cl.Cl
Synonym:
latrepirdine ; dimebon dihydrochloride ; dimebon (latrepirdine) ; dimebone ; dimebolin ; brn 0622478 ; dimebolin-dihydrochloride ; dimebon ; dimeboline ; preparation-84


Description

Dimebolin (hydrochloride), also known as Dimebon™, is an orally-available drug, approved in Russia for use as a non-selective antihistamine, that has shown promise in the treatment of neurodegenerative diseases, including Alzheimer's disease and Huntington's disease. In addition to preventing the onset and progression of disease by being neuroprotective, Dimebolin appears to promote clinical improvement by increasing cognitive function. At the cellular level, Dimebolin appears to have diverse effects, inhibiting the neurotoxic action of β-amyloid and acting as a calcium channel protein inhibitor, inhibiting NMDA-type glutamate receptors, and preventing mitochondrial leakage.,6,7 The hydrochloride form of Dimebolin is soluble in both aqueous and organic solvents.


Suppliers

Hangzhou Keying Chem Co., Ltd.
HKC15006000
BOC Sciences
BS6001800
Santa Cruz Biotechnology, Inc.
294348
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Prices & Availability




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Properties for Dimebolin dihydrochloride

Molecular Weight:
319.44 g·mol−1
Density:
1.13
Solubility:
Soluble in ethanol (~3 mg/ml), DMSO (~10 mg/ml), DMF (~1 mg/ml), PBS, pH 7.2 (~10 mg/ml), and water (>25 mg/ml).
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Safety & Transport Information

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Alternative Distributors of [Dimebolin dihydrochloride]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

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MSDS:
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