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3,3'-Diindolylmethane

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Formula: C17H14N2
CAS: 1968-05-4
search Element: diindolylmethane

Identification

Structural Formula
3,3'-Diindolylmethane
CAS:
1968-05-4
EINECS:
Molecular Formula:
C17H14N2
MDL:
MFCD00195766
SMILES:
C1=CC=C2C(=C1)C(=CN2)CC3=CNC4=CC=CC=C43
Synonym:
hb 236 ; diindole methane ; 3,3'-diindolymetane ; di-3-indolylmethane ; arundine ; 3-diindolyl methane ; indolyl-ch2-indolyl ; dim ; di indolyl methane ; indole dimer


Description

3,3'-Diindolylmethane is an anticancer and antineoplastic agent. 3,3'-Diindolylmethane induces apoptosis in human cancer cells. 3,3'-Diindolylmethane is also an activator of CYP (cytochrome P450) and Chk2 (checkpoint kinase 2) as well as a partial agonist of aryl hydrocarbon receptor (Ah Receptor). The compound is a dimer of indole-3-carbinol.


Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI14495796
Shandong Ench Chemical Co.,Ltd
SECC6303150
Shandong Minglang Chemical Co., Ltd
SMC7352940
Lori Industry Co., Ltd
LI4621386
Autech Industry Co.,Limited
AIC5672268
Shandong SanYoung Industry Co., Ltd
SSI7352940
Create Chemical Co., Ltd.
CC5251575
BLD Pharmatech Ltd
BP3781134
Ambeed, Inc.
A155014
Chemlyte Solutions
CS3781134
AIDP, Inc.
A210420
Arcadia Biotechnology
AB4411323
X´ian Taicheng Chem Co., Ltd
XTC6092436
Xiamen Equation Chemical Co.,Ltd
XECC6723360
Aecochem Corp.
AC294882
CSNpharm, Inc.
CSN19392
Hangzhou Lingrui Chemical Co., Ltd.
HLC7352940
Xiamen Hisunny Chemical Co., Ltd.
XHC6932772
AK Scientific, Inc.
AS3991197
Simagchem Corporation
SC4411323
Zehao Industry Co., Ltd.
ZI5041512
Leap Chem Co., Ltd
LC3781134
Santa Cruz Biotechnology, Inc.
204624
Dayang Chem (Hangzhou) Co.,Ltd.
DC6512604
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Angene International Limited
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Prices & Availability




Data is processed


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Properties for 3,3'-Diindolylmethane

Molecular Weight:
246.31 g·mol−1
Density:
1.27 g/cm3 (Predicted)
Melting point:
167 °C
Boiling point:
504.82° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (200 mg/ml), ethanol (50 mM), chloroform, and methanol. Insoluble in water.
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
Hazard Classes:
irritant
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
2-8 °C
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Alternative Distributors of [3,3'-Diindolylmethane]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Biosynth AG | Fischer Chemicals AG | Nanjing R&M Fine Chemical Co., Ltd. | BTX Global Pharmaceuticals, Inc. | 3B Scientific Corporation | Hangzhou FST Pharmaceutical Co., Ltd. | Nantong Chem-Tech. (Group) Co., Ltd. | Changzhou ODOC International Trade Co., Ltd. | Ningbo Pangs Chem Int'l Co., Ltd. | Unispec Chemicals Co. | Donboo Amino Acid Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai AOKChem Group Limited | Hangzhou Sage Chemical Co., Ltd. | TRUST&WE Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Anix-Chem Limited | Hangzhou Pharma & Chem Co. Ltd. | Jinan Great Chemical Co., Ltd. | Nantong Qihai Chemicals Co., Ltd. | Win-Win Chemical Co., Limited | Ruiyuan Group Limited | 3Way Pharm Inc. | Shanghai Insight Chemicals Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | All Right Chemical Co., Ltd. | Pharmfar Co., Ltd. | Beijing Yangguang Furuide Chemical Co., Ltd. | Watson International Ltd | Aopharm | Pangea Chemicals | Hubei Yuancheng Saichuang Tech.Co.,Ltd | Sciyu Biotech Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Green Fine Chemical (Shanghai) Co., Ltd. | Hangzhou Neway Chemicals Co., Ltd. | Intatrade Chemicals GmbH

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