(24R)-24,25-Dihydroxyvitamin D3 | CAS 55721-11-4

Element: dihydroxyvitamin

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C-S » Chemicals » dihydroxyvitamin-PX59803

Identification

(24R)-24,25-Dihydroxyvitamin D3

CAS:

55721-11-4

EINECS:

Molecular Formula:

C₂₇H₄₄O₃

MDL:

MFCD00941417

SMILES:

C[C@H](CC[C@H](C(C)(C)O)O)[C@H]1CC[C@@H]2[C@@]1(CCC/C2=CC=C/3C[C@H](CCC3=C)O)C

Synonym:

ro21-5816 ; (24r)-24,25-dihydroxyvitamin d3 ; (24r)-hydroxycalcidiol ; protein-tyrosine kinase receptor flk-1 ; 24(r),25-dihydroxycholecalciferol ; (24r)-24,25-dihydroxycholecalciferol ; kinase insert domain receptor ; osteod ; k-dr ; secalciferol

Description

(24R)-24,25-Dihydroxyvitamin D3 is a vitamin D3 metabolite which is involved in bone ossification. In addition, it is known that (24R)-24,25-Dihydroxyvitamin D3 mediates calcium and phosphorus homeostasis. Also (24R)-24,25-Dihydroxyvitamin D3 inhibits calcium channels in osteosarcoma cells via suppressing the effects of 1α, 25-dihydroxyvitamin D3 and testosterone. Alternate studies indicate that (24R)-24,25-Dihydroxyvitamin D3 can decrease the abundance of p53 and Pi-induced cytochrome c translocation. Furthermore, (24R)-24,25-Dihydroxyvitamin D3 can increase cell proliferation in resting zone (RC) chondrocytes and inhibits matrix enzymes by possibly inhibiting the degradation of the matrix.

Suppliers

Xiamen Equation Chemical Co.,Ltd

XECC396819840

Simagchem Corporation

SC26047812

Santa Cruz Biotechnology, Inc.

231276

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(24R)-24,25-Dihydroxycalciol

Chemlyte Solutions

CS15124536

(3R,6R)-6-((1R,3aS,7aR,e)-4-((Z)-2-((S)-5-hydroxy-2-methylenecyclohexylidene)ethylidene)-7a-methyloctahydro-1H-inden-1-yl)-2-methylheptane-2,3-diol

Shanghai Haoyuan Chemexpress Co., Ltd.

SHC139650558600

Prices & Availability

Data is processed

Properties for (24R)-24,25-Dihydroxyvitamin D3

Molecular Weight:

416.64 g·mol−1

Density:

~1.1 g/cm³ (Predicted)

Melting point:

63-65 °C

Boiling point:

~506.78° C (Predicted)

Solubility:

Soluble in methanol, and chloroform.

Safety & Transport Information

Risk Codes:

R28 - Very toxic if swallowed

Safety Codes:

S28 - After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Symbols:

T+

Storage temperature :

Amber Vial, -20 °C Freezer, Under Inert Atmosphere

RID/ADR certification :

2811

Alternative Distributors of [(24R)-24,25-Dihydroxyvitamin D3]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Clearsynth Canada INC.