Chemical-Suppliers Chemical-Suppliers

Dihydrolipoic acid

×
Formula: C8H16O2S2
CAS: 462-20-4
search Element: dihydrolipoic acid
Page Content Identification Properties Suppliers Prices & Availability Get Quick Quote ☰

Identification

Structural Formula
Dihydrolipoic acid
CAS:
462-20-4
EINECS:
Molecular Formula:
C8H16O2S2
MDL:
MFCD00166974
SMILES:
C(CCC(=O)O)CC(CCS)S
Synonym:
usaf xr-12 ; dihydro-lipoicaci ; dihydroliponsure ; dihydrolipoic acid ; reducedlipoicacid ; dihydrothiocticacid ; dihydrolipoate ; dihydro-thiocticaci ; dhla ; usafxr-12


Description

Dihydrolipoic acid is a carboxylic acid containing two thiols groups. It is known that the R enantiomer is biochemically significant. Dihydrolipoic acid is used as a component in hydrophilic nanomaterial preparations. Studies suggest that Dihydrolipoic acid induces apoptosis in mouse embryonic stem cells (ESC-B5) at 50-100μM concentrations. In addition, Dihydrolipoic acid increases reactive oxygen species (ROS), cytoplasmic free calcium and nitric oxide (NO) levels. This also leads to loss in mitochondrial membrane potential and activation of caspase-9 and caspase-3. Due to the amphipathic nature of the molecule it can act as an antioxidant in both hydrophilic and lipophilic environments.


Suppliers

JieJie Group Co., Ltd.
JG7922376
+
Alzchem Trostberg GmbH
AT7922376
+
Santa Cruz Biotechnology, Inc.
207581
Dayang Chem (Hangzhou) Co.,Ltd.
DC11164464
+
Get Quick Quote

CAS equal suppliers

γ-Lipoic Acid
Pharmaffiliates Analytics & Synthetics Pvt. Limited
PA 12 93510

Prices & Availability




Data is processed


x

Properties for Dihydrolipoic acid

Molecular Weight:
208.34 g·mol−1
Density:
~1.1 g/mL (Predicted)
Melting point:
98.06° C (Predicted)
Boiling point:
~360.8° C at 760 mmHg (Predicted)
x

Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
    • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Symbols:
Xi
Hazard symbol Xi
x

Alternative Distributors of [Dihydrolipoic acid]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

ABCR GmbH & Co. KG | Gihi Chemicals Co., Limited | Lanospharma Laboratories Co., Ltd. | Kinbester Co., Ltd. | Clearsynth Canada INC. | Shanghai Richem International Co., Ltd.

x

Downloads

Mol File:
-/-
MSDS:
-/-




View related products













▲
▲