Chemical-Suppliers Chemical-Suppliers

Y-27632 dihydrochloride

×
Formula: C14H21N3O.2HCl
CAS: 146986-50-7
search Element: dihydrochloride 27632
Page Content Identification Properties Suppliers Prices & Availability Get Quick Quote ☰

Identification

Structural Formula
Y-27632 dihydrochloride
CAS:
146986-50-7
EINECS:
Molecular Formula:
C14H21N3O.2HCl
MDL:
MFCD03490488
SMILES:
C[C@H](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl
Synonym:


Description

Y-27632 dihydrochloride is a selective Rho-kinase inhibitor, which suppresses cholinergic nerve-mediated contractions. In addition, studies show that Y-27632 dihydrochloride increases the release of neurotransmitters from cholinergic nerves. Studies conducted on smooth muscle preparations suggest that Y-27632 dihydrochloride suppresses nerve-mediated contractile responses stimulated by acetylcholine and noradrenaline. Furthermore, studies on lung tissue damage in rats suggest that Y-27632 dihydrochloride can restore the damage caused by oleic acid by inhibition of ROCK-1 and ROCK-2. Y-27632 dihydrochloride also inhibits protein kinase C related kinase, PRK2.


Suppliers

Aea.ltd
A322644
+
Autech Industry Co.,Limited
AIC12424968
+
Ambeed, Inc.
A101744
+
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI317412696
+
H&Z Industry Co.,Ltd
HIC9203680
+
Finetech Industry Limited
FIL11504600
+
Hefei Hirisun Pharmatech Co., Ltd
HR060244
+
AK Scientific, Inc.
AS8742622
+
Xingrui Industry Co., Limited
XIL13345336
+
BOC Sciences
BS5521656
+
Amadis Chemical Company Limited
ACCL14267130
+
Leap Chem Co., Ltd
LC8282484
+
Santa Cruz Biotechnology, Inc.
281642
Get Quick Quote

CAS equal suppliers

Y-27632
ShangHai Biochempartner Co., Ltd.
BCP01863
Y-27632
Pharmacore Co., Limited
PL161483
Y-27632
Ambeed, Inc.
A112358
Y-27632
Excenen Pharmatech Co., Ltd.
EX-A423
Y-27632
CSNpharm, Inc.
CSN12226
Y-27632
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI4831932
Y-27632
Aea.ltd
A4998
Y-27632
Chemlyte Solutions
CS126378
Y-27632, free base
Santa Cruz Biotechnology, Inc.
3536
Cyclohexanecarboxamide, 4-[(1r)-1-aminoethyl]-n-4-pyridinyl-, trans-
Angene International Limited
AGN-PC-0O3F2M
Cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-4-pyridinyl-, trans-
CM Fine Chemicals
CFC924836992
Cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-4-pyridinyl-, trans-
Sirius Fine Chemicals SiChem GmbH
SC-0048
(+)-(R)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride
Pt. Sarana Bela Nusa
PSBN1476073800

Prices & Availability




Data is processed


x

Properties for Y-27632 dihydrochloride

Molecular Weight:
338.28025 g·mol−1
Solubility:
Soluble in water (14 mg/mL), ethanol (~5 mg/mL), DMSO (~20 mg/mL), DMF (~30 mg/mL), PBS, pH 7.2 (~10 mg/mL), and methanol (25 mg/mL).
x

Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
    • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

x

Alternative Distributors of [Y-27632 dihydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Jinan Great Chemical Co., Ltd. | Shanghai Sun-shine Chemical Technology Co., Ltd. | ChengDu KaiXin Technology Development Co., Ltd. | BOC Sciences | Jinan Haohua Industry Co., Ltd.

x

Downloads

Mol File:
-/-
MSDS:
-/-




View related products













▲
▲