BD 1063 dihydrochloride | CAS 150208-28-9

Element: dihydrochloride 1063

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C-S » Chemicals » dihydrochloride-PX78517

Identification

BD 1063 dihydrochloride

CAS:

150208-28-9

EINECS:

Molecular Formula:

C₁₃H₁₈Cl₂N₂

MDL:

MFCD00792740

SMILES:

CN1CCN(CC1)CCC2=CC(=C(C=C2)Cl)Cl.Cl.Cl

Synonym:

BD 1063 ; ; Piperazine,1-[2-(3,4-dichlorophenyl)ethyl]-4-methyl-

Description

BD 1063 dihydrochloride is a selective antagonist of the σ receptors. Along with the agonist BD 1047, BD 1063 is demonstrated to attenuate the dystonia produced by the high affinity σ receptor ligands di-o-tolylguanidine and Haloperidol. BD 1063 and BD 1047 are described to have similar activity at the σ-1 receptor, and BD 1063 demonstrates less affinity at σ-2 than BD 1047. BD 1063 has been used as a tool to probe the relationship between the σ receptors and ethanol reinforcement.