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E-4031 dihydrochloride

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Formula: C21H27 N3 O3 S . 2 Cl H
CAS: 113559-13-0

Identification

Structural Formula
E-4031 dihydrochloride
CAS:
113559-13-0
EINECS:
Molecular Formula:
C21H27 N3 O3 S . 2 Cl H
MDL:
MFCD00889193
SMILES:
C1=CC(=CC=C1C(C2CCN(CC2)CCC3=NC(=CC=C3)C)=O)N([H])[S](C)(=O)=O.CCl.Cl[H].O([H])[H].O([H])[H]
Synonym:
Methanesulfonamide,N-[4-[[1-[2-(6-methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]-,dihydrochloride (9CI) ; E 4031 ; Methanesulfonamide,N-[4-[[1-[2-(6-methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]-,hydrochloride (1:2)


Description

E-4031 dihydrochloride is a K+ channel blocker. Lead compound to investigate class III antiarrhythmic drugs. E-4031 dihydrochloride is a specific blocker of delayed rectifier current (I(kr)). Blocks the human ether-a-go-go-related gene (HERG) at all pulse frequencies (frequency-independent block) without significant recovery at rest.


Suppliers

Santa Cruz Biotechnology, Inc.
203034
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CAS equal suppliers

E-4031
Hangzhou MolCore BioPharmatech Co.,Ltd.
MC34432
E-4031
ShangHai Biochempartner Co., Ltd.
BCP07766
E-4031
BOC Sciences
BS72216
E-4031
Aea.ltd
A4284
N-(4-(1-(2-(6-Methylpyridin-2-yl)ethyl)piperidine-4-carbonyl)phenyl)methanesulfonamide dihydrochloride
BLD Pharmatech Ltd
BP2203266096
N-[4-[[1-[2-(6-Methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]methanesulfonamide dihydrochloride
Leap Chem Co., Ltd
LC2457073710
N-[4-[[1-[2-(6-Methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]methanesulfonamide dihydrochloride
Finipharma Ltd
F1911038220

Prices & Availability




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Properties for E-4031 dihydrochloride

Molecular Weight:
510.47 g·mol−1
Solubility:
Soluble in water (100 mg/ml), and DMSO.
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Safety & Transport Information

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Alternative Distributors of [E-4031 dihydrochloride]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

Mol File:
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MSDS:
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