Identification
Molecular Formula:
C1 3 H1 5 N3 O2 S
SMILES:
C1CN(CCN1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl.Cl
Synonym:
iqsp ; ha-100 dihydrochloride ; 1-(5-isoquinolinylsulfonyl)-piperazin ; 1-(5-isoquinolinylsulfonyl)piperazine ; c-1 ; ha-100 hydrochloride ; 1-[(isoquinolin-5-yl)sulfonyl]piperazine ; 1-(5-isoquinolinylsulfonyl)piperazine 2hcl ; ha-100 ; 1-(5-isoquinolinesulfonyl)piperazine
Description
HA-100 is an isoquinoline compound with an added piperazinylsulfonyl group that acts as an inhibitor of protein kinases (PKs), including PKA, PKC, and PKG (IC50 = 8, 12, and 4 µM, respectively). It less effectively blocks the activity of myosin light chain kinase (IC50 = 240 µM).
Suppliers
Santa Cruz Biotechnology, Inc.
203072
Dayang Chem (Hangzhou) Co.,Ltd.
DC13645456
CAS equal suppliers
1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
Chemieliva Pharmaceutical Co., Ltd.
CP742022260
1-(5-Isoquinolinesulfonyl)piperazine, dihydrochloride
Wanko Chemical Co., Ltd.
WC508815264
Prices & Availability
Data is processed
Properties
Safety & Transport
Alternative Distributors
Downloads
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Properties for HA-100 dihydrochloride
Molecular Weight:
277.34 g·mol−1
Boiling point:
537.7° C at 760 mmHg (Predicted)
Solubility:
Soluble in water (10 mg/ml), and DMSO (35 mg/ml).
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Safety & Transport Information
Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical adviceS36 - Wear suitable protective clothing
Hazard Symbols:
Xi
Storage temperature :
-20°C
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Alternative Distributors of [HA-100 dihydrochloride]
Producers or manufacturers change the product range from time to time.
Currently there are no other manufacturers known.