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Diethyl Pyrocarbonate

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Formula: C6H10O5
CAS: 1609-47-8
search Element: pyrocarbonate diethyl
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Identification

Structural Formula
Diethyl Pyrocarbonate
CAS:
1609-47-8
EINECS:
216-542-8
Molecular Formula:
C6H10O5
MDL:
MFCD00009106
SMILES:
CCOC(=O)OC(=O)OCC
Synonym:
diethyl dicarbonate ; ethyl pyrocarbonate ; ethylpyrocarbonate ; baycovin ; depc ; diethylpyrokarbonat ; diethyl pyrocarbonat ; diethyl oxydiformate ; piref ; dkd


Description

Diethyl Pyrocarbonate has been shown to inhibit ryanodine binding to ryanodine/Ca2+ receptor channels in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles. This compound could be useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Diethyl Pyrocarbonate also inhibits PAF Acetylhydrolase (platelet-activating factor acetyl hydrolase), and has been used as a probe for the topography of 5.8S rRNA in yeast ribosomes.


Suppliers

Shandong Lanhai Industry Co.,Ltd.
SLIC13866930
+
H&Z Industry Co.,Ltd
HIC8403360
+
Autech Industry Co.,Limited
AIC11344536
+
BLD Pharmatech Ltd
BP7562268
+
Chemlyte Solutions
CS7562268
+
Ambeed, Inc.
A127898
+
Lori Industry Co., Ltd
LI9242772
+
Zhangjiagang Pharmabl Co., Ltd
ZP12603780
+
Serva Electrophoresis GmbH
SE10923276
Hangzhou Keying Chem Co., Ltd.
HKC12605040
+
Hangzhou Lingrui Chemical Co., Ltd.
HLC14705880
+
scienTEST - bioKEMIX GmbH
S-B10504200
+
Finetech Industry Limited
FIL10504200
+
Carbone Scientific Co., Ltd.
CS11763528
+
AK Scientific, Inc.
AS7982394
+
Xingrui Industry Co., Limited
XIL12184872
+
Zehao Industry Co., Ltd.
ZI10083024
+
Amadis Chemical Company Limited
ACCL13026510
+
Leap Chem Co., Ltd
LC7562268
+
Santa Cruz Biotechnology, Inc.
202574
Dayang Chem (Hangzhou) Co.,Ltd.
DC13025208
+
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Merck Schuchardt OHG
MSO7603040
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Xiamen Equation Chemical Co.,Ltd
XECC12166080
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Shandong SanYoung Industry Co., Ltd
SSI13305320
Diethylpyrocarbonate
Huateng Pharmaceutical Co.,Ltd
90893
Diethyl pyrocarbonate (DEPC)
Molekula
22057917
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Angene International Limited
AGN-PC-07A5H0
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Acros Organics BVBA
AOB18247296

Prices & Availability




Data is processed


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Properties for Diethyl Pyrocarbonate

Molecular Weight:
162.14 g·mol−1
Density:
1.12 g/mL at 20 °C
Boiling point:
93-94 °C18 mm Hg(lit.)
Flash point:
157 ºF
Solubility:
Soluble in chloroform, ethanol (50% w/w), esters, ketones, and hydrocarbons.Slowly soluble in water with hydrolytic decomposition yielding ethanol and CO2.
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
    • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S37/39 - Wear suitable gloves and eye/face protection
Hazard Classes:
6.1(b)
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
2-8°C
RID/ADR certification :
2810
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Alternative Distributors of [Diethyl Pyrocarbonate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | BOC Sciences | Pfaltz & Bauer, Inc. | Share Chemical Co., Ltd. | Jinan Great Chemical Co., Ltd. | Gihi Chemicals Co., Limited | Molekula GmbH | scienTEST | Jinan Haohua Industry Co., Ltd. | Longschem Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Suzhou Yacoo Chemical Reagent Corporation | Amadis Chemical Co., Ltd. | East Chemical Industry Co., Ltd. | Wanko Chemical Co., Ltd.

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