1,9-Dideoxyforskolin | CAS 64657-18-7

Element: dideoxyforskolin

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C-S » Chemicals » dideoxyforskolin-PX79116

Identification

1,9-Dideoxyforskolin

CAS:

64657-18-7

EINECS:

Molecular Formula:

C₂₂H₃₄ O₅

MDL:

MFCD00082318

SMILES:

CC(=O)O[C@H]1[C@H]([C@@H]2[C@](CCCC2(C)C)([C@@H]3[C@@]1(O[C@@](CC3=O)(C)C=C)C)C)O

Synonym:

1,9-dideoxyforskolin from coleusforskohl ii ; 7β-acetoxy-6β-hydroxy-8,13-epoxy-labd-14-en-11-one ; dideoxyforskolin ; forskolin, 1,9-dideoxy-, coleus forskohlii ; dideoxyforskolin, 1,9- ; 7beta-acetoxy-6beta-hydroxy-8,13-epoxy-labd-14-en-11-one ; (-)-1,9-dideoxyforskolin ; 1h-naphtho[2,1-b]pyran-1-one,5-(acetyloxy)-3-ethenyldodecahydro-6-hydroxy-3,4a,7,7,10a-pentamethyl-, [3r-(3a,4ab,5b,6b,6aa,10ab,10ba)]- ; forskolin, 1,9-dideoxy ; forskolin, 1,9-dideoxy isolated from col eus ; 1h-naphtho[2,1-b]pyran-1-one,5-(acetyloxy)-3-ethenyldodecahydro-6-hydroxy-3,4a,7,7,10a-pentamethyl-,(3r,4as,5s,6s,6as,10as,10br)- ; 1,9-dideoxyforskolin ; ddfsk

Description

1,9-Dideoxyforskolin is a derivative of Forskolin which unlike the parent compound is incapable of activating adenylate cyclase. Forskolin-induced stimulation of adenylate cyclase and increased cAMP levels is employed to study the modulation of ion channels and cAMP-dependent second messenger systems, and 1,9-Dideoxyforskolin serves as a negative control for cAMP-related Forskolin inductions. 1,9-Dideoxyforskolin mimics some activity of Forskolin, demonstrating alteration of K⁺ channel activity, reversal of doxorubicin resistance in multidrug resistant sarcoma cells, protection against TNF-α-mediated cytotoxicity, and desensitization at GABA_A receptors.

Suppliers

Evonik ( formerly Wilshire Technologies, Inc. )

E9603840

Sigma-Aldrich International GmbH

SI6401920

Leap Chem Co., Ltd

LC3601080

Santa Cruz Biotechnology, Inc.

201560

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Prices & Availability

Data is processed

Properties for 1,9-Dideoxyforskolin

Molecular Weight:

378.5024 g·mol−1

Density:

1.12 g/cm3

Melting point:

149-150°C

Boiling point:

455 °C at 760 mmHg

Flash point:

146.9 °C

Solubility:

methanol: 28 mg/mL

Physical Description:

solid

Safety & Transport Information

Storage temperature :

-20°C

Alternative Distributors of [1,9-Dideoxyforskolin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Cfm Oskar Tropitzsch GmbH

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MSDS:

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