5,7-Dichlorokynurenic acid | CAS 131123-76-7

Element: dichlorokynurenic acid

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Identification

5,7-Dichlorokynurenic acid

CAS:

131123-76-7

EINECS:

Molecular Formula:

C₁₀H₄Cl₂NNaO₃

MDL:

MFCD11045951

SMILES:

C1=C(C=C2C(=C1Cl)C(=O)C=C(N2)C(=O)O)Cl

Synonym:

2-quinolinecarboxylicacid, 5,7-dichloro-4-hydroxy- ; 5,7-dichloro-4-hydroxy-2-quinolinecarboxylic acid ; 5,7-dichlorokynurenic acid ; 5,7-dcka ; 5,7-dichlorokynurenic acid sodium salt ; 5,7-dichorokynurenic acid ; kynurenicacid, 5,7-dichloro- (4ci) ; 5,7-dichloroquinurenic acid ; 5,7-dichlorokynurenic acid potent excita tory ami ; 5,7-dichloro-4-hydroxyquinoline-2-carboxylic acid ; 5,7-dichlorokynurenic acid sodium ; 2-quinolinecarboxylic acid, 5,7-dichloro-4-hydroxy-

Description

5,7-Dichlorokynurenic acid is a derivative of the excitatory amino acid kynurenic acid and an antagonist of the strychnine-insensitive glycine modulatory (co-agonist) binding site on the NMDA receptor. 5,7-Dichlorokynurenic acid is described to potently and noncompetitively antagonize NMDA-stimulated elevation of cytosolic Ca²⁺, accumulation of cGMP, and release of norepinephrine. 5,7-Dichlorokynurenic acid is an inhibitor of GluR.

Suppliers

Santa Cruz Biotechnology, Inc.

200440

Dayang Chem (Hangzhou) Co.,Ltd.

DC16126448

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CAS equal suppliers

5,7-Dichlorokynurenic acid sodium salt

Santa Cruz Biotechnology, Inc.

sc-291018

2-Quinolinecarboxylic acid, 5,7-dichloro-4-hydroxy-

Angene International Limited

AGN-PC-0O0ZGC

Prices & Availability

Data is processed

Properties for 5,7-Dichlorokynurenic acid

Molecular Weight:

280.04 g·mol−1

Density:

1.651 g/cm3

Melting point:

171.07° C (Predicted)

Boiling point:

428.3 °C at 760 mmHg

Flash point:

212.8 °C

Solubility:

0.1 M NaOH: soluble

Safety & Transport Information

Risk Codes:

R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

Storage temperature :

Desiccate at RT

Alternative Distributors of [5,7-Dichlorokynurenic acid]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Abcam Biochemicals plc (formaly Ascent Scientific Ltd.)

Downloads

Mol File:

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MSDS:

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