7,8-dichloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid | CAS 300675-28-9

Element: quinolinecarboxylic dichloro dihydro acid

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C-S » Chemicals » dichloro-dihydro-oxo-quinolinecarboxylic-acid-PX55004

Identification

7,8-dichloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

CAS:

300675-28-9

EINECS:

Molecular Formula:

C₁₀H₅Cl₂NO₃

MDL:

MFCD01911608

SMILES:

C1=CC(=C(C2=C1C(=O)C(=CN2)C(=O)O)Cl)Cl

Synonym:

3-Quinolinecarboxylic acid, 7,8-dichloro-1,4-dihydro-4-oxo-

Description

7,8-dichloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid is a casein kinase 2 (CK2) inhibitor.CK2 is a serine/threonine-selective protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis and its activity is increased in many tumors and proliferating tissues, which lends promise as an anti-cancer drug target. CAY10577 inhibits CK2 with an IC50 value of 0.8 µM.

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Santa Cruz Biotechnology, Inc.

223742

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Prices & Availability

Data is processed

Properties for 7,8-dichloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

Molecular Weight:

258.1 g·mol−1

Density:

~1.7 g/cm³ (Predicted)

Melting point:

304° C (Predicted)

Boiling point:

~448.3° C at 760 mmHg (Predicted)

Solubility:

Soluble in DMSO (~0.15 mg/ml), and DMF (~0.5 mg/ml).

Safety & Transport Information

coming up soon

Alternative Distributors of [7,8-dichloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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Mol File:

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MSDS:

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