2,4-Diamino-6-hydroxypyrimidine | CAS 56-06-4

Element: hydroxypyrimidine diamino

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C-S » Chemicals » diamino-hydroxypyrimidine-PX75142

Identification

2,4-Diamino-6-hydroxypyrimidine

CAS:

56-06-4

EINECS:

200-254-4

Molecular Formula:

C₄H₆N₄O

MDL:

MFCD00006098

SMILES:

C1(=CC(N=C(N1[H])N([H])[H])=O)N([H])[H]

Synonym:

timtec-bb sbb004252 ; 6-aminoisocytosine ; nsc 9302 ; aurora ka-376 ; nsc 680818 ; dahp ; 2,4-diaminohypoxanthine ; 2,4-diamino-6-hydroxy ; nsc 44914 ; akos msc-0109

Description

2,4-Diamino-6-hydroxypyrimidine is a selective inhibitor of GCH-I (GTP cyclohydrolase I). Suppression of this enzyme by 2,4-Diamino-6-hydroxypyrimidine impedes tetrahydrobiopterin biosynthesis and abolishes both lipopolysaccharide-induced elevation of biopterin levels and lipopolysaccharide-induced NO synthesis. 2,4-Diamino-6-hydroxypyrimidine is also described to inhibit D-erythro-7,8-dihydroneopterintriphosphate synthetase activity.

Suppliers

FUDI Chemical Co. Ltd.

FCC13645456

Lori Industry Co., Ltd

LI13644092

H&Z Industry Co.,Ltd

HIC12404960

Create Chemical Co., Ltd.

CC15504650

Chemlyte Solutions

CS11163348

Autech Industry Co.,Limited

AIC16746696

MedicalChem (Yancheng) Manuf. Co., Ltd.

M24187254

Evonik ( formerly Wilshire Technologies, Inc. )

E297611904

Xiamen Equation Chemical Co.,Ltd

XECC19849920

Shanghai UCHEM Inc.

UCHEM-6634

Merck Schuchardt OHG

MSO12404960

Hangzhou Lingrui Chemical Co., Ltd.

HLC21708680

Hefei Hirisun Pharmatech Co., Ltd

HR131018

CM Fine Chemicals

CFC10544216

AK Scientific, Inc.

AS11783534

DSL Chemicals (Shanghai) Co., Ltd.

C003080

Simagchem Corporation

SC13023906

Xingrui Industry Co., Limited

XIL17987192

Capot Chemical Co., Ltd.

7054

Zehao Industry Co., Ltd.

ZI14884464

Leap Chem Co., Ltd

LC11163348

Santa Cruz Biotechnology, Inc.

202404

Dayang Chem (Hangzhou) Co.,Ltd.

DC19227688

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CAS equal suppliers

2,6-diaminopyrimidin-4-ol

Manchester Organics Limited

B54213

2,6-Diaminopyrimidin-4-ol

Sancai Industry Co.,Ltd.

SIC12004800

2,6-Diaminopyrimidin-4(1H)-one

Hangzhou MolCore BioPharmatech Co.,Ltd.

CS16285

2,6-Diaminopyrimidin-4(1H)-one

Wanko Chemical Co., Ltd.

WC21606480

2,6-Diaminopyrimidin-4(1H)-one

CSNpharm, Inc.

CSN23265

4(1H)-pyrimidinone, 2,6-diamino-

Angene International Limited

AGN-PC-0JK6E7

4(1H)-Pyrimidinone, 2,6-diamino-

Evonik Industries AG

EIA19207680

2,4-Diamino-6-hydroxypyrimidine 96%

Acros Organics BVBA

AOB13305320

2,4-Diamino-6-hydroxypyrimidine, 96%

Alfa (A Johnson Matthey Company)

A23046912

Prices & Availability

Data is processed

Properties for 2,4-Diamino-6-hydroxypyrimidine

Molecular Weight:

126.12 g·mol−1

Density:

1.60 g/cm³ (Predicted)

Melting point:

285-286 °C (dec.)(lit.)

Boiling point:

523.96° C at 760 mmHg (Predicted)

Solubility:

Soluble in DMSO (14 mg/ml), methanol, water (11.5 g/L at 20° C), PBS pH 7.2 (~3.3 mg/ml), ethanol, and DMF (14 mg/ml).

Safety & Transport Information

Risk Codes:

R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

Storage temperature :

Desiccate at +4 °C

Alternative Distributors of [2,4-Diamino-6-hydroxypyrimidine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified