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O-Desmorpholinopropyl Gefitinib

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Formula: C15H11ClFN3O2
CAS: 184475-71-6

Identification

Structural Formula
O-Desmorpholinopropyl Gefitinib
CAS:
184475-71-6
EINECS:
Molecular Formula:
C15H11ClFN3O2
MDL:
MFCD09908046
SMILES:
COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)O
Synonym:
4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol ; gefitinib intermediate 1 ; 4-(3-chlor-4-fluorophenylamino)-7-methoxyquinazolin-6-ol ; 4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinol ; faah-in-2 ; o-desmorpholinopropyl gefitinib ; gefitinib intermediate vii ; gefitinib impurity c ; 4-(3-chloro-4-fluoroanilino)-6-hydroxy-7-methoxyquinazoline ; n-(3-chloro-4-f


Description

O-Desmorpholinopropyl Gefitinib is a metabolite of Gefitinib, which is a potent inhibitor of tyrosine phosporylation in EGFR.


Suppliers

Santa Cruz Biotechnology, Inc.
212456
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CAS equal suppliers

FAAH-IN-2
Ambeed, Inc.
A207764
FAAH-IN-2
CSNpharm, Inc.
CSN11599
Gefitinib impurity C
Salsbury Chemicals, Inc.
SC14404320
Gefitinib metabolite P
Salsbury Chemicals, Inc.
SC15844752
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
AK Scientific, Inc.
AS649819494
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Dayang Chem (Hangzhou) Co.,Ltd.
DC1060242408
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Shanghai Mintchem Development Co., Ltd.
SMD1333853352
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Simagchem Corporation
SC718221546
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
CM Fine Chemicals
CFC581423256
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Chemieliva Pharmaceutical Co., Ltd.
CP1197035910
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Leap Chem Co., Ltd
LC615618468
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Hangzhou J&H Chemical Co., Ltd.
HJC1060242408
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Zhejiang Hongxin Chemical
ZHC855034200
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Skyrun Industrial Co., Ltd.
SI923427702
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Haihang Industry Co., Ltd.
HI889226676
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Xiamen Hisunny Chemical Co., Ltd.
XHC1128645144
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Wanko Chemical Co., Ltd.
WC820824624
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
ShangHai Biochempartner Co., Ltd.
BCP14414
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Ascender Chemical Co.,Ltd
ACC855034200
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
FUDI Chemical Co. Ltd.
FCC752430096
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Xingrui Industry Co., Limited
XIL991839672
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Gihi Chemicals Co., Limited
GCL923436936
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Autech Industry Co.,Limited
AIC923436936
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Allfluoro Pharmaceutical Co. Ltd.
APC1128645144
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI2359894392
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Xiamen Equation Chemical Co.,Ltd
XECC1094454720
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Shandong SanYoung Industry Co., Ltd
SSI1197047880
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
BLD Pharmatech Ltd
BP615618468
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Chemlyte Solutions
CS615618468
4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-ol
Hangzhou MolCore BioPharmatech Co.,Ltd.
CS11817
6-Quinazolinol, 4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-
Angene International Limited
AGN-PC-0D0J0J

Prices & Availability




Data is processed


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Properties for O-Desmorpholinopropyl Gefitinib

Molecular Weight:
319.72 g·mol−1
Melting point:
>260 °C (dec.)
Solubility:
Soluble in DMSO
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Storage temperature :
-20 °C Freezer
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Alternative Distributors of [O-Desmorpholinopropyl Gefitinib]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Suzhou Bichal Biological Technology Co., Ltd. | Clearsynth Canada INC.

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