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9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (potassium salt)

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Formula: C23H38 O4 . K
CAS: 122576-55-0

Identification

Structural Formula
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (potassium salt)
CAS:
122576-55-0
EINECS:
Molecular Formula:
C23H38 O4 . K
MDL:
SMILES:
CCCC/C=CCC1C(=C)​CC(O)​[C@@H]​1/C=C/C(O)​C(C)​(C)​CCCC
Synonym:
u-46785b ; metenprost potassium ; 9-deoxy-9-methylene-16,16-dimethyl prostaglandin e2, potassium salt ; 9-methylene-11alpha,15r-dihydroxy-16,16-dimethyl-prosta-5z,13e-dien-1-oic acid, potassium salt ; 11,15-dihydroxy-16,16-dimethyl-9-methyleneprosta-5,13-dien-1-oic acid monopotassium salt, (5z,11alpha,13e,15r)- ; prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-methylene-, monopotassium salt, (5z,11alpha,13e,15r)- ; meteneprostpotassium ; u 46785b ; prosta-5,13-dien-1-oicacid, 11,15-dihydroxy-16,16-dimethyl-9-methylene-, monopotassium salt, (5z,11a,13e,15r)- (9ci)


Description

9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (potassium salt) (Metenprost potassium) is a potent analog of 16,16-Dimethyl-prostaglandin E2 which is an antisecretory, antiulcer Prostaglandin E2 (PGE2) analog with potent cytoprotective activity that binds to PGDH (prostaglandin dehydrogenase or HPGD), but is resistant to metabolism, thereby inhibiting the enzyme. This compound has been shown to terminate early pregnancy, but was found to be ineffective during the third trimester in monkey testing.


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Properties for 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (potassium salt)

Molecular Weight:
416.6358 g·mol−1
Boiling point:
520.5 °C at 760 mmHg
Flash point:
282.6 °C
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Mol File:
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MSDS:
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