15-deoxy-δ12,14-Prostaglandin D2 | CAS 85235-11-6

Element: prostaglandin delta deoxy

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C-S » Chemicals » deoxy-delta-prostaglandin-PX65452

Identification

15-deoxy-δ12,14-Prostaglandin D2

CAS:

85235-11-6

EINECS:

Molecular Formula:

C₂₀H₃₀O₄

MDL:

SMILES:

CCCCC/C=C/C=C1C(=O) CC(O) C1C/C=CCCCC(=O) O

Synonym:

15-deoxy-delta12,14-prostaglandin d2 ; 15-deoxy-Î”12,14-prostaglandin d2 ; 9alpha,hydroxy-11-oxo-prosta-5z,12e,14e-trien-1-oic acid

Description

A synthetic analog of PGD₂ and a potential precursor to the PPARγ ligand 15-deoxy-Δ12,14-PGJ2.1 Exhibits cytotoxic effects on L1210 murine leukemia cells in vitro. 15-deoxy-Δ12,14-PGD₂ is 10-fold more potent than PGD₂ in this activity.2 However, it is a l