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Decarestrictine D

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Formula: C10H16 O5
CAS: 127393-89-9
search Element: decarestrictine

Identification

Structural Formula
Decarestrictine D
CAS:
127393-89-9
EINECS:
Molecular Formula:
C10H16 O5
MDL:
MFCD00887071
SMILES:
C[C@@H]1C[C@@H](/C=C[C@@H]([C@H](CC(=O)O1)O)O)O
Synonym:
2H-Oxecin-2-one,3,4,5,8,9,10-hexahydro-4,5,8-trihydroxy-10-methyl-, [4S-(4R*,5R*,6E,8R*,10S*)]- ; (-)-Decarestrictine D ; Decarestrictin D ; Decarestrictine D ; SM 133 ; Tuckolide ; 2H-Oxecin-2-one,3,4,5,8,9,10-hexahydro-4,5,8-trihydroxy-10-methyl-, (4S,5S,6E,8S,10R)-


Description

Decarestrictine D is a 10-membered lactone which potently inhibits cholesterol biosynthesis and shows hypolipidemic activity. Studies indicate that the absolute stereochemistry of Decarestrictine D is in the S-conformation at carbon 3 bearing the hydroxyl group. Alternate studies show that Decarestrictine D does not inhibit HMGCoA reductase (HMGCR) in order to impede cholesterol biosynthesis. Furthermore, under acidic conditions Decarestrictine D can be synthesized from the Decarestrictines A1 and A2 in addition to the creation of other side products.


Suppliers

Santa Cruz Biotechnology, Inc.
202571
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CAS equal suppliers

Tuckolide
Leap Chem Co., Ltd
LC162486

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Properties for Decarestrictine D

Molecular Weight:
216.231 g·mol−1
Density:
1.28 g/cm3 (Predicted)
Melting point:
121-123°C (dichloromethane hexane )
Boiling point:
442.69° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO, methanol, and acetone.
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Alternative Distributors of [Decarestrictine D]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Cfm Oskar Tropitzsch GmbH

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