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N-Deacetylcolchiceine

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Formula: C19H21 N O5
CAS: 3482-37-9
search Element: deacetylcolchiceine
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Identification

Structural Formula
N-Deacetylcolchiceine
CAS:
3482-37-9
EINECS:
Molecular Formula:
C19H21 N O5
MDL:
SMILES:
COC1=CC2=C(C(OC)=C1OC)C1=CC=C(O)C(=O)C=C1[C@@H](N)CC2
Synonym:
trimethylcolchicinic acid ; nsc 36796 ; benzo[a]heptalen-9(5h)-one,7-amino-6,7-dihydro-10-hydroxy-1,2,3-trimethoxy-, (s)- ; aids-002892 ; trimethyl-colchicinicaci ; colchicinic acid, o,o',o''-trimethyl- (6ci,7ci) ; desacetylcholchiceine ; colchiceine,n-deacetyl- (8ci) ; desacetylcolchiceine ; benzo[a]heptalen-9(5h)-one,7-amino-6,7-dihydro-10-hydroxy-1,2,3-trimethoxy-, (7s)- ; deacetylcolchiceine ; n-deacetylcolchiceine ; n-deacetyl-colchicein ; deacetylcholchiceine ; aids002892


Description

Antimitotic agent disrupting microtubule action through the binding of tubulin and preventing polymerization. Has been shown to stimulate the intrinsic GTPase activity of tubulin. Induces apoptosis and activates the JNK/SAPK signals.


Suppliers

Santa Cruz Biotechnology, Inc.
208016
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CAS equal suppliers

Trimethylcolchicinic acid
Gihi Chemicals Co., Limited
GCL13505400

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Data is processed


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Properties for N-Deacetylcolchiceine

Molecular Weight:
343.41 g·mol−1
Density:
1.32 g/cm3
Melting point:
>230°C (dec.)
Boiling point:
629°C at 760 mmHg
Flash point:
334.2°C
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Safety & Transport Information

Poison by intraperitoneal route. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also COLCHICINE.
Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
Safety Codes:
S36 - Wear suitable protective clothing
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
-20°C
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Alternative Distributors of [N-Deacetylcolchiceine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Clearsynth Canada INC.

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Downloads

Mol File:
-/-
MSDS:
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