Chemical-Suppliers Chemical-Suppliers

Daunorubicin hydrochloride

×
Formula: C27H29NO10.HCl
CAS: 23541-50-6
search Element: hydrochloride daunorubicin
Page Content Identification Properties Suppliers Prices & Availability Get Quick Quote ☰

Identification

Structural Formula
Daunorubicin hydrochloride
CAS:
23541-50-6
EINECS:
245-723-4
Molecular Formula:
C27H29NO10.HCl
MDL:
MFCD04974507
SMILES:
C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)C)O)N)O.Cl
Synonym:
ondena ; daunoblastine ; daunoblastin ; daunomycin hcl ; ndc0082-4155 ; daunoblastina ; daunorubicin hcl ; 23541-50-6 ; daunomycine hcl ; cerubidine


Description

Daunorubicin hydrochloride is a DNA intercalating anthracylcine natural product isolated from Streptomyces peucetius. Upon intercalation, Daunorubicin forms stable complexes with the DNA backbone, inhibiting normal functioning of the double helix and the proteins that interact with it. Daunorubicin is nearly identical in structure to Doxorubicin, with Doxorubicin containing a pendant hydroxyl group on the exocyclic ketone. The action of Daunorubicin has been correlated to efficacy in suppressing the proliferation of certain acute leukemias. Daunorubicin hydrochloride is an inhibitor of Topo I and Topo II and an activator of LASS.


Suppliers

Aea.ltd
A364728
+
Ambeed, Inc.
A148164
+
Shandong SanYoung Industry Co., Ltd
SSI18207280
+
Nantong Xindao Biotech Ltd
NXB13525408
+
Aozeal Certified Standards (AOCS), Inc.
D0057.00
+
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI358814352
+
H&Z Industry Co.,Ltd
HIC10404160
+
Autech Industry Co.,Limited
AIC14045616
+
Alfa (A Johnson Matthey Company)
A16644992
Xiamen Equation Chemical Co.,Ltd
XECC16648320
+
scienTEST - bioKEMIX GmbH
S-B13005200
+
Finetech Industry Limited
FIL13005200
+
Carbone Scientific Co., Ltd.
CS14564368
+
Xingrui Industry Co., Limited
XIL15086032
+
BOC Sciences
BS6241872
+
Amadis Chemical Company Limited
ACCL16128060
+
Santa Cruz Biotechnology, Inc.
200921
Dayang Chem (Hangzhou) Co.,Ltd.
DC16126448
+
Get Quick Quote

CAS equal suppliers

Daunomycin
Salsbury Chemicals, Inc.
SC240720
Daunorubicin HCl
Hainan Zhongxin Chemical Co., Ltd.
HZC10884352
Daunorubicin HCl
Santa Cruz Biotechnology, Inc.
sc-200921
Daunorubicin HCl
Chemieliva Pharmaceutical Co., Ltd.
CP11203360
Daunorubicin HCl
Leap Chem Co., Ltd
LC5761728
Daunorubicin HCl
Hangzhou J&H Chemical Co., Ltd.
HJC9923968
Daunorubicin HCl
Sigma-Aldrich International GmbH
SI10243072
Daunorubicin HCl
Medibro Corporation Limited
MCL8643456
Daunorubicin HCl
Skyrun Industrial Co., Ltd.
SI8642592
Daunorubicin HCl
LGM Pharma
LP320960
Daunorubicin HCl
Haihang Industry Co., Ltd.
HI8322496
Daunorubicin HCl
Wanko Chemical Co., Ltd.
WC7682304
Daunorubicin HCl
CSNpharm, Inc.
CSN16731
Daunomycin hydrochloride
Hangzhou Cherry Pharmaceutical Technology Co., Ltd.
HCPT244812240
Daunorubicin Hydrochloride; RP 13057 Hydrochloride; Daunomycin
Excenen Pharmatech Co., Ltd.
EX-A2649
(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride
BLD Pharmatech Ltd
BP68904206712

Prices & Availability




Data is processed


x

Properties for Daunorubicin hydrochloride

Molecular Weight:
563.98 g·mol−1
Melting point:
190 °C (dec)
Solubility:
Soluble in water (≥113), methanol, ethanol (≥10), and DMSO (≥72 mg/mL).
x

Hazard Statements

GHS06

GHS06
Toxic
  • Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3
GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R40 - Limited evidence of a carcinogenic effect
R42/43 - May cause sensitization by inhalation and skin contact
Safety Codes:
S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S37/39 - Wear suitable gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Classes:
6.1(b)
Hazard Symbols:
Xn, Xi
Hazard symbol Xn Hazard symbol Xi
Storage temperature :
-20°C
RID/ADR certification :
UN 2811 6.1 / PG 3
x

Alternative Distributors of [Daunorubicin hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Molekula GmbH | Nantong Chem-Tech. (Group) Co., Ltd. | China Yangzhou Wandong Medical Co., Ltd. | ShangHai Biochempartner Co., Ltd. | Discovery Fine Chemicals Limited | Jinan Wedo Industrial Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Wuxi Mizat Chemical Technology Co., Ltd. | Shanghai Rainbow Chemicals Co., Ltd. | Wuhan Sunrise Technology Development Company Ltd. | Jinan Great Chemical Co., Ltd. | Bichem Lab Co., Ltd. | East Chemical Industry Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | API Vanguard | Yongyi Chemicals Group Co., Ltd. | Aopharm | Xiamen Hisunny Chemical Co., Ltd. | scienTEST | Gihi Chemicals Co., Limited | Clearsynth Canada INC. | Wanko Chemical Co., Ltd.

x

Downloads

Mol File:
-/-
MSDS:
-/-

















▲
▲