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Cyclophosphamide Monohydrate

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Formula: C7H15Cl2N2O2P . H2O
CAS: 6055-19-2
search Element: cyclophosphamide monohydrate
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Identification

Structural Formula
Cyclophosphamide Monohydrate
CAS:
6055-19-2
EINECS:
Molecular Formula:
C7H15Cl2N2O2P . H2O
MDL:
MFCD00149395
SMILES:
C1CNP(=O)(OC1)N(CCCl)CCCl.O
Synonym:
endoxanmonohydrate ; timtec-bb sbb003026 ; cyclophosphamide , ctx ; cyclophosphamide mon ; -2monohydrate ; procy-tox ; endoxon ; cpa ; cytoxan ; cycloblastin


Description

Cyclophosphamide monohydrate is an alkylating, cytotoxic agent experimentally shown to crosslink DNA, causing strand breakage and inducing mutations. It is also believed to possess immunosuppressive properties. Cyclophosphamide Monohydrate inhibits ALDH1 (aldehyde dehydrogenase 1) through its degradation product acrolein, as well as induces apoptosis in the rat thymus via the Fas/Fas ligand pathway.


Suppliers

Ambeed, Inc.
A143958
+
CSNpharm, Inc.
CSN10723
Sigma-Aldrich International GmbH
SI17925376
+
Hefei Hirisun Pharmatech Co., Ltd
HR130411
+
Leap Chem Co., Ltd
LC10083024
+
Santa Cruz Biotechnology, Inc.
202117
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Dayang Chem (Hangzhou) Co.,Ltd.
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Santa Cruz Biotechnology, Inc.
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AK Scientific, Inc.
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Aecochem Corp.
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Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
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Gihi Chemicals Co., Limited
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Simagchem Corporation
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H&Z Industry Co.,Ltd
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BOC Sciences
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Finetech Industry Limited
FIL13005200
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Xiamen Equation Chemical Co.,Ltd
XECC16648320
Cyclophosphamide 1-hydrate
Chemlyte Solutions
CS9362808
Cyclophosphamide monohydrate, 97%
Acros Organics BVBA
AOB12545016
Cyclophosphamide monohydrate, 97+%
Alfa (A Johnson Matthey Company)
A21766528
2-(Bis(2-chloroethyl)amino)-1,3,2-oxazaphosphinane 2-oxide hydrate
BLD Pharmatech Ltd
BP950428512

Prices & Availability




Data is processed


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Properties for Cyclophosphamide Monohydrate

Molecular Weight:
279.1 g·mol−1
Melting point:
49-51 °C(lit.)
Flash point:
>230 ºF
Solubility:
H2O: 0.1 g/mL, clear, colorless
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Hazard Statements

GHS06

GHS06
Toxic
  • Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3
GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R25 - Toxic if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R45 - May cause cancer
R46 - May cause inheritable genetic damage
R61 - May cause harm to the unborn child
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S37/39 - Wear suitable gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use
Hazard Classes:
6.1
Hazard Symbols:
T
Hazard symbol T
Storage temperature :
2-8°C
RID/ADR certification :
UN 3464 6.1 / PG 3
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Alternative Distributors of [Cyclophosphamide Monohydrate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Inter-Chemical Ltd. | Olainfarm | Molekula GmbH | Hallochem Pharma Co., Ltd. | 3B Scientific Corporation | Longschem Co., Ltd. | ABCR GmbH & Co. KG | Nantong Chem-Tech. (Group) Co., Ltd. | Changzhou Sinly Pharmchem Co., Ltd. | CCS. CHEM. Co., Ltd. | New Dragon Industrial Co., Ltd | Suzhou Rovathin Pharmatech Co., Ltd | TRUST&WE Co., Ltd. | Shanghai Boyle Chemical Co., Ltd. | Jinan Great Chemical Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | BOC Sciences | Finetech Industry Limited | Jinan Haohua Industry Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | scienTEST | Gihi Chemicals Co., Limited | Clearsynth Canada INC.

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