Cyclopamine-KAAD | CAS 306387-90-6

Element: cyclopamine kaad

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C-S » Chemicals » cyclopamine-kaad-PX60569

Identification

Cyclopamine-KAAD

CAS:

306387-90-6

EINECS:

Molecular Formula:

C₄₄H₆₃N₃O₄

MDL:

SMILES:

CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(=O)CCC6(C5CC4=C3C)C)C)N(C1)CCNC(=O)CCCCCNC(=O)CCC7=CC=CC=C7

Synonym:

3-keto-n-aminoethyl-n'-aminocaproyldihydrocinnamoyl cyclopamine, >80%

Description

Cyclopamine-KAAD is a potent, cell-permeable analog of Cyclopamine that specifically inhibits the Hedgehog (Hh) signaling with similar or lower toxicity. Cyclopamine-KAAD binds to SmoA1 and promotes its exit from the endoplasmic reticulum. Cyclopamine-KAAD also suppresses both the ShhNp-induced pathway activity and SmoA1-induced reporter activity.

Suppliers

Santa Cruz Biotechnology, Inc.

221448

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CAS equal suppliers

3-Keto-N-aminoethyl-N'-aminocaproyldihydrocinnamoyl cyclopamine

Salsbury Chemicals, Inc.

SC30249072

Prices & Availability

Data is processed

Properties for Cyclopamine-KAAD

Molecular Weight:

697.999 g·mol−1

Density:

1.16 g/cm³ (Predicted)

Boiling point:

875.60° C at 760 mmHg (Predicted)

Solubility:

Soluble in water (partly ), DMSO (5 mg/ml), methanol (1 mg/ml), and ethanol (1 mg/ml).

Safety & Transport Information

Storage temperature :

Hygroscopic, -20 °C Freezer, Under Inert Atmosphere

Alternative Distributors of [Cyclopamine-KAAD]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

Downloads

Mol File:

-/-

MSDS:

-/-