(-)-Cotinine | CAS 486-56-6 | Chemical-Suppliers

Element: cotinine

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C-S » Chemicals » cotinine-PX69046

Identification

(-)-Cotinine

CAS:

486-56-6

EINECS:

207-634-9

Molecular Formula:

C₁₀H₁₂N₂O

MDL:

MFCD00077696

SMILES:

CN1[C@H](CCC1=O)C2=CN=CC=C2

Synonym:

(?)-cotinine solution ; nih 10498 ; cotinine(rg) ; s-(-)-cotinine ; (-)-cotinine,98% ; l-cotinine ; (-)cotinine methanol solution ; (-)-cotinine ; (s)-2-pyrrolidinon ; cotinine

Description

(-)-Cotinine is a major nicotine metabolite. (-)-Cotinine has been shown to activate a subpopulation of α3/ α6β2 nAChRs in monkey striatum. It has a long pharmacological half-life (15-19 hours) compared to that of nicotine (2-3 hours). (-)-Cotinine binds nicotinic- and muscarinic-type acetylcholine receptors with minimal receptor desensitization and demonstrates antipsychotic drug-like properties in behavioral models, neuroprotective properties in neurodegenerative disease models, and enhances attention in a delayed matching-to-sample task.

Suppliers

Xingrui Industry Co., Limited

XIL6962784

Santa Cruz Biotechnology, Inc.

205267

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Cotinine

Pharmaffiliates Analytics & Synthetics Pvt. Limited

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CL9242772

S-(-)-Cotinine

Haihang Industry Co., Ltd.

HI10923276

(-)-Cotinine, 98%

Alfa (A Johnson Matthey Company)

A10883264

Nicotine EP Impurity C ( Cotinine)

Aozeal Certified Standards (AOCS), Inc.

N0021.06

2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, (5s)-

Angene International Limited

AGN-PC-0OAVQ4

S-(-)-Cotinine ((5S)-(-)-1-Methyl-5-(3-pyridiyl)-2-pyrrolidinone)

United States Biological

C7904-49A

Prices & Availability

Data is processed

Properties for (-)-Cotinine

Molecular Weight:

176.22 g·mol−1

Melting point:

40-42 °C(lit.)

Boiling point:

250 °C150 mm Hg(lit.)

Flash point:

>230 ºF

Solubility:

Soluble in water (partly), DMSO (100 mM), ethanol (50 mg/ml, yielding a clear, faint yellow to yellow solution), methanol, and chloroform.

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R22 - Harmful if swallowed
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S7 - Keep container tightly closed

Hazard Symbols:

Xn, Xi, T, F
Hazard symbol T

Storage temperature :

2-8°C

RID/ADR certification :

UN 1230 3 / PG 2

Alternative Distributors of [(-)-Cotinine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences