Coomassie Blue R-250 | CAS 6104-59-2

Element: coomassie blue

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C-S » Chemicals » coomassie-blue-PX74155

Identification

Coomassie Blue R-250

CAS:

6104-59-2

EINECS:

228-060-5

Molecular Formula:

C₄₅H₄₄N₃NaO₇S₂

MDL:

MFCD00041762

SMILES:

CCN(CC1=CC(=CC=C1)S(=O)(=O)[O-])C2=CC=C(C=C2)C(=C3C=CC(=[N+](CC)CC4=CC(=CC=C4)S(=O)(=O)[O-])C=C3)C5=CC=C(C=C5)NC6=CC=C(C=C6)OCC.[Na+]

Synonym:

acid cyanine 6b ; page blue 83 ; serva blue r ; r-250 ; c.i.acidblue83 ; derminaazure6b ; cbb r-250 ; ci no 42660 ; acid blue 83 ; ci 42660

Description

Coomassie Blue R-250 is a triphenylmethane dye used extensively in SDS-PAGE for the analysis of proteins. The dye molecule binds to proteins to form a protein-dye complex. This complex stabilizes the negatively charged anionic form of the dye producing the blue color, even under acidic conditions. Coomassie Blue R-250 is additionally used in the Bradford Assay to quantify the concentration of protein in a solution, such as cell lysates.

Suppliers

Santa Cruz Biotechnology, Inc.

24972

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Prices & Availability

Data is processed

Properties for Coomassie Blue R-250

Molecular Weight:

825.97 g·mol−1

Melting point:

174-180 °C

Flash point:

14 °C

Safety & Transport Information

Risk Codes:

R10 - Flammable
R11 - Highly flammable
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R36/38 - Irritating to eyes and skin
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Symbols:

F, T, Xn, Xi
Hazard symbol T