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Clofibrate

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Formula: C12H15ClO3
CAS: 637-07-0
search Element: clofibrate

Identification

Structural Formula
Clofibrate
CAS:
637-07-0
EINECS:
211-277-4
Molecular Formula:
C12H15ClO3
MDL:
MFCD00000615
SMILES:
CCOC(=O)C(C)(C)OC1=CC=C(C=C1)Cl
Synonym:
cpib ; elpi ; epib ; lip1 ; artes ; yoclo ; lip.1 ; apolan ; bresit ; clofar


Description

Clofibrate is a ligand agonist for PPARα (peroxisome proliferator-activated receptor α), or an inducer of cytochromes P450’s CYP4A1 and CYP4A3. In studies utilizing rats treated with Clofibrate, cytochromes CYP4A1 and CYP4A3 are reported to be expressed in the liver. Further studies of CYP4A1 and CYP4A3 expression in rat liver indicated that these enzymes are able to catalyze oxidation of fatty acids and prostaglandins. Also offered as a deuterium-labelled compound, Clofibrate-d4


Suppliers

Ambeed, Inc.
A533783
Shandong Minglang Chemical Co., Ltd
SMC3501400
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI6902760
Xiamen Equation Chemical Co.,Ltd
XECC3201600
CSNpharm, Inc.
CSN11481
Hangzhou Lingrui Chemical Co., Ltd.
HLC3501400
Sigma-Aldrich International GmbH
SI320960
AK Scientific, Inc.
AS190570
Leap Chem Co., Ltd
LC180540
Santa Cruz Biotechnology, Inc.
200721
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Angene International Limited
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Prices & Availability




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Properties for Clofibrate

Molecular Weight:
242.7 g·mol−1
Density:
1.14 g/mL at 25 °C(lit.)
Boiling point:
154 °C
Flash point:
113 °C
Solubility:
Soluble in ethanol (25 mg/ml), DMSO (25 mg/ml), acetone, chloroform, ether, hexane, DMF (>50 mg/ml), and ethanol:PBS (1:6, pH 7.2) (0.1 mg/ml). Insoluble in water.
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Safety & Transport Information

Risk Codes:
R22 - Harmful if swallowed
R37/38 - Irritating to respiratory system and skin
R40 - Limited evidence of a carcinogenic effect
R41 - Risk of serious damage to eyes
R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S61 - Avoid release to the environment. Refer to special instructions/safety data sheet
Hazard Symbols:
Xn, N
Hazard symbol N Hazard symbol Xn
Storage temperature :
2-8°C
RID/ADR certification :
UN 3082 9 / PG 3
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Alternative Distributors of [Clofibrate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Inter-Chemical Ltd. | Standard Chem. & Pharm. Co., Ltd | Taicang Qianjing Chemical Factory | Hallochem Pharma Co., Ltd. | Xiang Ding Chemical International Co., Ltd | Nantong Chem-Tech. (Group) Co., Ltd. | Jinan Great Chemical Co., Ltd. | Tai Hua Industries Co., Limited | Nantong Qihai Chemicals Co., Ltd. | Zouping Mingxing Chemical Co., Ltd. | Suzhou Sibian Chemical Technology Co., Ltd. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Pharmfar Co., Ltd. | BOC Sciences | Jinan Haohua Industry Co., Ltd. | Gihi Chemicals Co., Limited | Haihang Industry Co., Ltd. | Clearsynth Canada INC.

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