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Clemastine fumarate

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Formula: C21H26ClNO.C4H4O4
CAS: 14976-57-9
search Element: clemastine fumarate

Identification

Structural Formula
Clemastine fumarate
CAS:
14976-57-9
EINECS:
239-055-2
Molecular Formula:
C21H26ClNO.C4H4O4
MDL:
MFCD00137486
SMILES:
C[C@@](C1=CC=CC=C1)(C2=CC=C(C=C2)Cl)OCC[C@H]3CCCN3C.C(=C/C(=O)O)C(=O)O
Synonym:
reconin ; agasten ; tavegyl ; lecasol ; trabest ; alagyl ; hs592 ; piloral ; tavist ; tavegil


Description

Clemastine fumarate is a selective histamine H1 Receptor antagonist with IC50 of 3 nM. Clemastine Fumarate inhibits histamine induced rise in [Ca2+]i in HL-60 cells with an IC50 of 3 nM. Clemastine Fumarate significantly potentiates ATP-induced increase in [Ca2+]i in HEKhP2X7 cells not relying on histamine receptor blockage but on sensitizing P2X7 receptor.


Suppliers

Ambeed, Inc.
A157173
FUDI Chemical Co. Ltd.
FCC8363344
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI262210488
Shandong Minglang Chemical Co., Ltd
SMC13305320
Lori Industry Co., Ltd
LI8362508
H&Z Industry Co.,Ltd
HIC7603040
Shandong SanYoung Industry Co., Ltd
SSI13305320
Chemlyte Solutions
CS6842052
IPOCHEM Sp. z o.o.
ISZO6843420
Xiamen Equation Chemical Co.,Ltd
XECC12166080
Aecochem Corp.
AC5321596
CSNpharm, Inc.
CSN10663
Hangzhou Lingrui Chemical Co., Ltd.
HLC13305320
Sigma-Aldrich International GmbH
SI12163648
Pharmacore Co., Limited
PL8742622
AK Scientific, Inc.
AS7222166
Xingrui Industry Co., Limited
XIL11024408
Leap Chem Co., Ltd
LC6842052
Santa Cruz Biotechnology, Inc.
203897
Dayang Chem (Hangzhou) Co.,Ltd.
DC11784712
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CAS equal suppliers

Clemastinefumarate
Huateng Pharmaceutical Co.,Ltd
80007774
(2E)-but-2-enedioic acid; (2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine
Salsbury Chemicals, Inc.
SC41616124848

Prices & Availability




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Properties for Clemastine fumarate

Molecular Weight:
459.96 g·mol−1
Melting point:
158-162 °C
Boiling point:
154° C at 0.02 mmHg
Solubility:
Soluble in water (5 mM), methanol, DMSO (35 mg/ml), ethanol (3 mg/ml), and alcohol (slightly).
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Safety & Transport Information

Storage temperature :
Store at RT
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Alternative Distributors of [Clemastine fumarate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Inter-Chemical Ltd. | CCS. CHEM. Co., Ltd. | Hallochem Pharma Co., Ltd. | Nantong Chem-Tech. (Group) Co., Ltd. | All Right Chemical Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Anix-Chem Limited | Hangzhou Pharma & Chem Co. Ltd. | Jinan Great Chemical Co., Ltd. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Hubei Yuancheng Saichuang Tech.Co.,Ltd | Watson International Ltd | BOC Sciences | Taizhou Creating Chemical Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Clearsynth Canada INC.

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