Ciproxifan hydrochloride | CAS 1049741-81-2

Element: hydrochloride ciproxifan

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C-S » Chemicals » ciproxifan-hydrochloride-PX39702

Identification

Ciproxifan hydrochloride

CAS:

1049741-81-2

EINECS:

Molecular Formula:

C₁₆H₁₈N₂O₂.HCl

MDL:

MFCD08705321

SMILES:

C1CC1C(=O)C2=CC=C(C=C2)OCCCC3=CN=CN3.Cl

Synonym:

Description

Ciproxifan belongs to a novel chemical series of histamine H3-receptor antagonists. In vitro, it behaved as a competitive antagonist at the H3 autoreceptor controlling 3H histamine release from synaptosomes and displayed similar Ki values (0.5-1.9 nM) at the H3 receptor controlling the electrically-induced contraction of guinea pig ileum or at the brain H3 receptor labeled with 125I-iodoproxyfan. This appears to be an orally bioavailable, extremely selective and potent H3-receptor antagonist whose vigilance- and attention-promoting effects are promising for therapeutic applications in aging disorders.

Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI331213248

Santa Cruz Biotechnology, Inc.

257245

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CAS equal suppliers

Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone hydrochloride

Leap Chem Co., Ltd

LC1182635478

Cyclopropyl-[4-[3-(1h-imidazol-5-yl)propoxy]phenyl]methanone;hydrochloride

Angene International Limited

AGN-PC-00SM9L

Prices & Availability

Data is processed

Properties for Ciproxifan hydrochloride

Molecular Weight:

306.79 g·mol−1

Solubility:

Soluble in DMSO: 30 mg/mL: water, high purity: 30 mg/mL

Safety & Transport Information

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Alternative Distributors of [Ciproxifan hydrochloride]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

Downloads

Mol File:

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MSDS:

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