Cinacalcet Hydrochloride | CAS 364782-34-3

Element: hydrochloride cinacalcet

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C-S » Chemicals » cinacalcet-hydrochloride-PX79749

Identification

Cinacalcet Hydrochloride

CAS:

364782-34-3

EINECS:

Molecular Formula:

C₂₂H₂₃ClF₃N

MDL:

MFCD08067750

SMILES:

C[C@H](C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F.Cl

Synonym:

cinacalcet hydrochlodide ; amg-073 hcl ; cinacalcet (r-enantiomer) hcl ; n-[(1r)-1-naphthalen-1-yleth ; amg 073 (hydrochloride) ; cinacalcet hydrochloride ; cinacalcet hydrochloride, >=99% ; cinacalcet hcl ; cinacalcet hcl,amg073 ; amg-073 hcl (cinacalcet hcl)

Description

Cinacalcet Hydrochloride is a type II calcimimetic agent which controls calcium levels in cells by allosteric activation of CaSR (calcium sensing receptors). Studies show that Cinacalcet Hydrochloride affects cell proliferation in CHO cells transfected with CaSRs. In addition, it is known that Cinacalcet Hydrochloride inhibits the secretion of the parathyroid hormone (PTH). These studies suggest that Cinacalcet Hydrochloride in instrumental in increasing the cytoplasmic concentration of Ca²⁺. Furthermore, Cinacalcet Hydrochloride is an analog of NPS R-568 which contains a much better metabolic profile.

Suppliers

Ambeed, Inc.

A164114

Aozeal Certified Standards (AOCS), Inc.

C0036.00

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI331213248

Allfluoro Pharmaceutical Co. Ltd.

APC15846336

Shandong SanYoung Industry Co., Ltd

SSI16806720

Hangzhou Cherry Pharmaceutical Technology Co., Ltd.

HCPT244812240

Xiamen Equation Chemical Co.,Ltd

XECC15367680

Daming Changda Co., Ltd.

DC11523456

Aecochem Corp.

AC6722016

AK Scientific, Inc.

AS9122736

Xingrui Industry Co., Limited

XIL13925568

Capot Chemical Co., Ltd.

18298

Leap Chem Co., Ltd

LC8642592

Santa Cruz Biotechnology, Inc.

207438

Dayang Chem (Hangzhou) Co.,Ltd.

DC14885952

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United States Biological

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Prices & Availability

Data is processed

Properties for Cinacalcet Hydrochloride

Molecular Weight:

393.88 g·mol−1

Melting point:

175-177 °C

Boiling point:

440.9° C at 760 mmHg

Solubility:

Soluble in water (1 mg/ml at 25° C), DMSO (79 mg/ml at 25° C), ethanol (33 mg/ml at 25° C), and methanol.

Safety & Transport Information

Storage temperature :

-20 °C Freezer

Alternative Distributors of [Cinacalcet Hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

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