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8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphate sodium salt

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Formula: C16H14ClN5O7PS Na
CAS: 51239-26-0

Identification

Structural Formula
8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphate sodium salt
CAS:
51239-26-0
EINECS:
Molecular Formula:
C16H14ClN5O7PS Na
MDL:
MFCD00674888
SMILES:
[Na+].NC1=NC2=C(N=C(SC3=CC=C(Cl)C=C3)N2[C@@H]2O[C@@H]3COP([O-])(=O)O[C@H]3[C@H]2O)C(=O)N1
Synonym:
8-(4-chlorophenylthio)guanosine*3':5'-cyclicmono ; 8-(4-chlorophenylthio)guanosine-3',5'-cyclicmonophosphate(8-pcpt-cgmp),sodiumsalt ; 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3':5'-CYLIC MONOPHOSPHATE SODIUM SALT ; 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT ; 8-PCPT-CGMP NA ; 8-PCPT-CGMP SODIUM SALT ; 8-PCPT-CGMP TEA ; CGMP, 8-PCPT-, NA


Description

8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphate sodium salt (8-CPT-2'-O-Me-cAMP• Na ) is a selective activator of cGKI α, cGKI β, and cGKII (cGMP-dependent protein kinase (PKG) Iα, Iβ, and type II )as well as of CNG (cGMP-gated ion channels). The compounds higher activation potential as compared to cGMP, and retains excellent cell membrane permeability and phosphodiesterase stability. 8-CPT-2'-O-Me-cAMP • Na has been preferred alternative to unsuitable analogs such as dibutyryl-cGMP.


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Santa Cruz Biotechnology, Inc.
202029
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Properties for 8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphate sodium salt

Molecular Weight:
509.79 g·mol−1
Solubility:
Soluble in water (25 mg/ml). Insoluble in acetone.
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Alternative Distributors of [8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphate sodium salt]

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