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Charybdotoxin

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Formula: C176H277 N57 O55 S7
CAS: 95751-30-7
search Element: charybdotoxin

Identification

Structural Formula
Charybdotoxin
CAS:
95751-30-7
EINECS:
Molecular Formula:
C176H277 N57 O55 S7
MDL:
MFCD00146378
SMILES:
CC(C)CC(C(=O)NC(CC1CNCN1)C(=O)NC(CC(=O)N)C(=O)NC(C(C)O)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CS)C(=O)NC(CCSC)C(=O)NC(CC(=O)N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CS)C(=O)NC(CCCNC(=N)N)C(=O)NC(CS)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CO)C(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C(CS)NC(=O)C(C(C)C)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CS)NC(=O)C(CCC(=O)O)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(C(C)O)NC(=O)C(CS)NC(=O)C(CO)NC(=O)C(C(C)C)NC(=O)C(CC(=O)N)NC(=O)C(C(C)O)NC(=O)C(CC5=CC=CC=C5)NC(=O)C(CCC(=O)O)N
Synonym:
charybdotoxin (reduced),cyclic (7® ; charybdotoxin chtx ; charybdotoxin, recombinant, e coli ; m.w. 4295.89 c176h277n57o55s7 ; rchtx ; 33),(17® ; charybdotoxin ; 33,34,70,71,95,96-hexathia-2,5,8,11,14,17,20,23,26,29,37,40,43,46,49,52,55,58,61,64,67,74,77,80,83,86,89,92-octacosaazatricyclo[34.32.25.413,79]heptanonacontane,cyclic peptide deriv. ; 36: pn: wo2006116156 seqid: 36 claimed protein ; 35)-tris(disulfide) ; rcharybdotoxin ; chtx ; charybdotoxin, recombinant ; charybdotoxin, leiurus quinquestriatus hebraeus ; charybdotoxin (leiurus quinquestriatus hebraeus) ; 28),(13® ; pyr-ftnvscttskecwsvcqrlhntsrgkcmnkkcrcys


Description

Charybdotoxin is a peptide found in the venom of the scorpion Leiurus quinquestriatus. MaxiK (High, BK) or IK1 (intermediate) conductance calcium-activated and Kv1.3 (voltage-gated channel) inhibitor. A potent and selective blocker of the large conductance Ca2+-activated K+, Slo channels in nanomolar concentrations as well as Kv1.2 (Kd = 14 nM) and Kv1.3 (Kd = 2.6 nM) channels. Present in GH3 anterior pituitary cells and primary bovine aortic smooth muscle cells.


Suppliers

Alpha Biopharmaceuticals Co., Ltd.
AB4421326
Bachem AG
H-9595.0100
Acinopeptide Co., Ltd.
A286572
BOC Sciences
BS156468
Leap Chem Co., Ltd
LC234702
Santa Cruz Biotechnology, Inc.
200979
Dayang Chem (Hangzhou) Co.,Ltd.
DC4031612
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Properties for Charybdotoxin

Molecular Weight:
4295.89 g·mol−1
Solubility:
Solution at 1 mg/ml in Water
Physical Description:
white powder
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Safety & Transport Information

Storage temperature :
-20°C
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Alternative Distributors of [Charybdotoxin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Watson International Ltd | Chem-Impex International, Inc. | Shanghai Hanhong Chemical Co., Ltd. | Jinan Haohua Industry Co., Ltd.

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