Chartreusin | CAS 6377-18-0 | Chemical-Suppliers

Element: chartreusin

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C-S » Chemicals » chartreusin-PX76921

Identification

Chartreusin

CAS:

6377-18-0

EINECS:

Molecular Formula:

C₃₂H₃₂O₁₄

MDL:

MFCD00467138

SMILES:

C[C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)OC2=CC=CC3=C2C4=C5C6=C(C=CC(=C6C(=O)O4)C)OC(=O)C5=C3O)O[C@@H]7[C@@H]([C@H]([C@H]([C@H](O7)C)O)OC)O)O)O

Synonym:

u-7257 ; nsc5159 ; chartreusin ; lambdamycin ; antibioticx-465a ; chartreusin from streptomyces*chartreusis ; lambdamycin, nsc 5159, 747, 1293, x465a, g 261a ; 10-[[6-deoxy-2-o-(6-deoxy-3-o-methyl-?-d-galactopyranosyl)-?-d-galactopyranosyl]oxy]-6-hydroxy-1-methylbenzo[h][1]benzopyrano[5,4,3-cde][1]benzopyran-5,12-dione

Description

Chartreusin is a potent anti-proliferative agent originally derived from Streptomyces chartreusis. This compound has been shown to be a potent inhibitor of the catalytic activity of Topo II (topoisomerase II). Experiments have reported that Chartreusin binds to GC-rich tracts in DNA, inhibits RNA synthesis, and causes single-strand scission of DNA via formation of free radicals. Additionally, this agent has been shown to inhibit formation of several DNA-protein complexes.

Suppliers

Santa Cruz Biotechnology, Inc.

202994

Dayang Chem (Hangzhou) Co.,Ltd.

DC3411364

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Lambdamycin

Leap Chem Co., Ltd

LC198594

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Data is processed

Properties for Chartreusin

Molecular Weight:

640.59 g·mol−1

Density:

1.6 g/cm³ (Predicted)

Melting point:

185 °C

Solubility:

Soluble in water (partly miscible), and acetone.

Safety & Transport Information

Risk Codes:

R40 - Limited evidence of a carcinogenic effect

Safety Codes:

S22 - Do not breathe dust
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Symbols:

Storage temperature :

2-8°C

Alternative Distributors of [Chartreusin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Cfm Oskar Tropitzsch GmbH

Downloads

Mol File:

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MSDS:

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