Castanospermine | CAS 79831-76-8

Element: castanospermine

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C-S » Chemicals » castanospermine-PX72371

Identification

Castanospermine

CAS:

79831-76-8

EINECS:

Molecular Formula:

C₈H₁₅ N O₄

MDL:

MFCD00017555

SMILES:

C1CN2C[C@@H]([C@H]([C@@H]([C@H]2[C@H]1O)O)O)O

Synonym:

castanospermine castanospermum australe seeds ; castanospermine ; castanospermine, castanospermum australe ; castanospermine ,98% ; 1,6,7,8-indolizinetetrol,octahydro-, [1s-(1a,6b,7a,8b,8ab)]- ; (1s,6s,7r,8r,8ar)-1,6,7,8-tetrahydroxy-& ; 1,6,7,8-tetrahydroxyoctahydroindolizine ; (1s,6s,7r,8ar)-tetrahydroxyoctahydroindolizine ; castanospermine from castanospermum austral ; (8aα)-octahydroindolizine-1β,6α,7β,8α-tetrol ; castanospermin ; (+)-castanospermine

Description

Castanospermine, originally derived from Castanosperum australe has been shown to be a potent inhibitor of almond emulsion β-glucosidase, and also to inhibit fungal β-xylosidase. Other studies show castanospermine to have the capacity to make viral glycopeptides more susceptible to enzyme treatment. Additionally, castanospermine may have the potential ability to inhibit syncytium formation between HIV-infected and CD4-expressing cells and may also interfere with infectivity. It has also been demonstrated that this agent inhibits inflammation at the level of leukocyte extravasation in rat models of experimental adjuvant-induced arthritis and autoimmune encephalomyelitis. Castanospermine is an inhibitor of Glucosidase I, Maltase-glucoamylase, and MANBA.

Suppliers

Autech Industry Co.,Limited

AIC4051620

Santa Cruz Biotechnology, Inc.

201358

Dayang Chem (Hangzhou) Co.,Ltd.

DC4651860

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CAS equal suppliers

Castanospermine, 99%

Alfa (A Johnson Matthey Company)

A6401920

1,6,7,8-Indolizinetetrol,octahydro-, (1S,6S,7R,8R,8aR)-

Salsbury Chemicals, Inc.

SC924027720

Prices & Availability

Data is processed

Properties for Castanospermine

Molecular Weight:

189.21 g·mol−1

Density:

~1.5 g/cm³ (Predicted)

Melting point:

213-217 °C(lit.)

Boiling point:

~421.9° C at 760 mmHg (Predicted)

Solubility:

1 M HCl: 20 mg/mL, clear, very faintly yellow

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:

R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

Xn, Xi

Storage temperature :

2-8°C

Alternative Distributors of [Castanospermine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Downloads

Mol File:

-/-

MSDS:

-/-

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Castanospermine, 99%

castanospermine from castanospermum australe seeds