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Carboplatin

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Formula: C6H12N2O4Pt
CAS: 41575-94-4
search Element: carboplatin

Identification

Structural Formula
Carboplatin
CAS:
41575-94-4
EINECS:
255-446-0
Molecular Formula:
C6H12N2O4Pt
MDL:
MFCD00070464
SMILES:
C1CC(C1)(C(=O)[O-])C(=O)[O-].N.N.[Pt+4]
Synonym:
cbdca ; carboplat ; nsc-241240 ; carbopaltin ; carbonplatin ; carboplatin ; jm-8 ; carboplatinum ; ercar ; paraplatin


Description

Carboplatin is a second generation potent platinum-based antineoplastic agent that is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. The development of carboplatin was inspired from the efficacy of its progenitor, Cisplatin, the first of this class of antineoplastic agents. Carboplatin displays potent antitumor activity and lower nephrotoxicity than Cisplatin. The action of this group of platinum-based compounds is primarily attributed to DNA adduct formation, however, these molecules also bind other biological molecules, including enzymes, which might play a role in their mechanism of action.


Suppliers

Chemlyte Solutions
CS198594
H&Z Industry Co.,Ltd
HIC220880
Aozeal Certified Standards (AOCS), Inc.
C0091.00
Autech Industry Co.,Limited
AIC2971188
Forum Products Ltd.
FP209627
Guangzhou Topwork Chemical Co., Ltd.
GTC3961584
Alfa (A Johnson Matthey Company)
A3521056
Xiamen Equation Chemical Co.,Ltd
XECC3521760
Hainan Zhongxin Chemical Co., Ltd.
HZC3741496
Daming Changda Co., Ltd.
DC264792
CSNpharm, Inc.
CSN10551
Hangzhou Keying Chem Co., Ltd.
HKC3301320
scienTEST - bioKEMIX GmbH
S-B2751100
Hangzhou Ocean Chemical Co., Ltd.
HOC3631452
Finetech Industry Limited
FIL2751100
Hefei Hirisun Pharmatech Co., Ltd
HR130397
AK Scientific, Inc.
AS209627
Xingrui Industry Co., Limited
XIL3191276
BOC Sciences
BS132396
Leap Chem Co., Ltd
LC198594
Santa Cruz Biotechnology, Inc.
202093
Dayang Chem (Hangzhou) Co.,Ltd.
DC3411364
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Prices & Availability




Data is processed


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Properties for Carboplatin

Molecular Weight:
371.25 g·mol−1
Melting point:
228-230 °C
Solubility:
Soluble in water (10 mg/ml), saline, DMSO (<1 mg/ml), and ethanol (<1 mg/ml).
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization
GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:
R20/21 - Harmful by inhalation and in contact with skin
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R42/43 - May cause sensitization by inhalation and skin contact
R46 - May cause inheritable genetic damage
R61 - May cause harm to the unborn child
Safety Codes:
S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use
Hazard Symbols:
T
Hazard symbol T
Storage temperature :
Store at RT
RID/ADR certification :
2811
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Alternative Distributors of [Carboplatin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Advance Scientific & Chemical, Inc. | Inter-Chemical Ltd. | Santec Chemicals Corp. | Rongkang Industry Co.,Ltd - (NSTU Chemicals Hanggzhou Co.,) | Molekula GmbH | Hangzhou Onicon Chemical Co., Ltd. | Hallochem Pharma Co., Ltd. | Jiangsu Guotai International Group Co., Ltd. | Tai Hua Industries Co., Limited | Keen Union International Limited | Shanghai Chemicals & Pharmaceuticals Co., Limited | Nantong Chem-Tech. (Group) Co., Ltd. | Vesino Industrial Co., Ltd. | Pharmasi Chemicals Co., Ltd. | Ningbo Pangs Chem Int'l Co., Ltd. | TCI Europe NV | Changzhou An-Yuan Imp. & Exp. Corporation | Unispec Chemicals Co. | ShangHai Biochempartner Co., Ltd. | Abtonsmart Chemicals Co., Ltd. | Hangzhou Hysen Pharma Co., Ltd. | Jinan Wedo Industrial Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai AOKChem Group Limited | Suzhou Rovathin Pharmatech Co., Ltd | Shanghai Richem International Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Nantong Wanrong International Trading Co., Ltd. | Hangzhou Pharma & Chem Co. Ltd. | Lanospharma Laboratories Co., Ltd. | Shanghai Boyle Chemical Co., Ltd. | Junwee Chemical Co., Ltd. | Jinan Great Chemical Co., Ltd. | ZhangJiaGang CAE International Trading Co., Ltd. | Suzhou Sibian Chemical Technology Co., Ltd. | Ruiyuan Group Limited | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | API Vanguard | Watson International Ltd | Hubei Yuancheng Saichuang Tech.Co.,Ltd | Aopharm | BOC Sciences | Sunbow Biotech Ltd. | Finetech Industry Limited | Jinan Haohua Industry Co., Ltd. | Trademax Phamaceuticals & Chemicals Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Clearsynth Canada INC. | scienTEST | Wanko Chemical Co., Ltd. | Haihang Industry Co., Ltd.

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