Carbenicillin disodium salt

Carbenicillin disodium salt is a penicillin-derived, β-lactam antibiotic which inhibits the synthesis of peptidoglycan, a key component of the bacterial cell wall. In studies investigating the roles of biogenic polyamines, spermidine and spermine, on antibiotic susceptibility of several microorganisms it was observed that the mean inhibitory concentration (MIC) of β-lactam antibiotics such as Carbenicillin was decreased with the addition of spermidine and spermine to cultures of Escherichia coli and Salmonella enterica. Additionally, in plants Carbenicillin was investigated for its effects on morphology and growth of Beta vulgaris, Capsicum annuum and Glehnia littoralis roots. In this study, Carbenicillin was noted to inhibit root elongation while promoting root branching in contrast to Ampicillin.