BYK 191023 dihydrochloride | CAS 608880-48-4

Element: dihydrochloride 191023

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Identification

BYK 191023 dihydrochloride

CAS:

608880-48-4

EINECS:

Molecular Formula:

C₁₄H₁₄N₄O.2ClH

MDL:

MFCD11100187

SMILES:

COC1=CC(=NC=C1)CCC2=NC3=C(N2)C=CC=N3.Cl.Cl

Synonym:

1h-imidazo[4,5-b]pyridine, 2-[2-(4-methoxy-2-pyridinyl)ethyl]- ; 2-[2-(4-methoxy-2-pyridinyl)ethyl]-1h-imidazo[4,5-b]pyridinedihydrochloride ; byk 191023 dihydrochloride

Description

BYK 191023 dihydrochloride is a potent and selective inhibitor of NOS2 (IC₅₀ values are 86, 17000, 162000 nM for NOS2, NOS1, and NOS2, respectively). BYK 191023 acts in an NADPH^- and time-dependent manner.