Bumetanide (Ro 10-6338) | CAS 28395-03-1

Element: bumetanide 6338

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C-S » Chemicals » bumetanide-PX81121

Identification

Bumetanide (Ro 10-6338)

CAS:

28395-03-1

EINECS:

249-004-6

Molecular Formula:

C₁₇H₂₀N₂O₅S

MDL:

MFCD00078949

SMILES:

CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2

Synonym:

burine ; fontego ; pf1593 ; segurex ; bumex ; lixil ; bufenox ; pf159 ; burinex ; donald

Description

Bumetanide (Ro 10-6338) is a specific inhibitor of Na⁺-K⁺-2Cl^- cotransporter NKCC1, which has been shown to bind with high affinity and saturate binding of the cotransporter. The inhibitor has been reported to bind to different cell membranes, including HeLa cells, vascular muscle cells, endothelial cell, erythrocyte cells, and colonic adenocarcinoma cells, among others. Furthermore, Bumetanide has been observed to block the depolarization of GABA in cortical development studies.

Suppliers

Santa Cruz Biotechnology, Inc.

200727

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Prices & Availability

Data is processed

Properties for Bumetanide (Ro 10-6338)

Molecular Weight:

364.42 g·mol−1

Density:

~1.3 g/cm³ (Predicted)

Melting point:

230-2310C

Boiling point:

~571.24° C at 760 mmHg (Predicted)

Safety & Transport Information

Storage temperature :

Store at RT

Alternative Distributors of [Bumetanide (Ro 10-6338)]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified