3-Bromopyruvic acid | CAS 1113-59-3

Element: bromopyruvic acid

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C-S » Chemicals » bromopyruvic-acid-PX42609

Identification

3-Bromopyruvic acid

CAS:

1113-59-3

EINECS:

214-206-5

Molecular Formula:

C₃H₃BrO₃

MDL:

MFCD00002587

SMILES:

C(C(=O)C(=O)O)Br

Synonym:

bromopyruvicacidhydrate ; bromo-pyruvicaci ; 3-bromopyruvic acid ,97% ; 3-bromopyruvate ; beta-bromopyruvicacid ; nsc 11731 ; bromopyruvic acid ; 3-bromopyruvic acid ; bromopyruvate ; nsc 62343

Description

3-Bromopyruvic acid is a brominated derivative of pyruvic acid, which inhibits HXK II (hexokinase II) in cancer cells. As a result of this inhibition the cells are unable to metabolize glucose into ATP directly. Studies conducted on MCF-7 breast cancer cells show that 3-Bromopyruvic acid hydrate reduces the expression of Bcl-2, c-Myc and mutant p53, which are involved in the cell death signal transduction pathway. Alternate studies indicate that 3-Bromopyruvic acid hydrate is a very selective antibiotic, inhibiting the growth of certain yeasts.

Suppliers

Create Chemical Co., Ltd.

CC9502850

BLD Pharmatech Ltd

BP6842052

Ambeed, Inc.

A376712

Shandong Lanhai Industry Co.,Ltd.

SLIC12546270

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI262210488

Shandong SanYoung Industry Co., Ltd

SSI13305320

Nantong Xindao Biotech Ltd

NXB9883952

Kingreat Chemistry Company Limited

KCCL12926460

Richman Chemical Inc.,

RCI8363344

Quzhou Rundong Chemical Co., Ltd.

QRC12545016

Hainan Zhongxin Chemical Co., Ltd.

HZC12925168

Daming Changda Co., Ltd.

DC9122736

CSNpharm, Inc.

CSN12486

scienTEST - bioKEMIX GmbH

S-B9503800

Carbone Scientific Co., Ltd.

CS10643192

Xiamen Hisunny Chemical Co., Ltd.

XHC12545016

AK Scientific, Inc.

AS7222166

Simagchem Corporation

SC7982394

Amadis Chemical Company Limited

ACCL11785890

Santa Cruz Biotechnology, Inc.

260854

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Huateng Pharmaceutical Co.,Ltd

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A14084224

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Hangzhou J&H Chemical Co., Ltd.

HJC251110044

Prices & Availability

Data is processed

Properties for 3-Bromopyruvic acid

Molecular Weight:

166.96 g·mol−1

Density:

~2.0 g/cm³ (Predicted)

Melting point:

77-82 °C

Boiling point:

~223.4° C at 760 mmHg (Predicted)

Solubility:

Soluble in water (100 mg/ml), DMSO, ethyl acetate, and water.

Hazard Statements

GHS05
Corrosive

Corrosive to metals, category 1

Safety & Transport Information

Risk Codes:

R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R34 - Causes burns

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S27 - Take off immediately all contaminated clothing
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Classes:

Hazard Symbols:

Storage temperature :

2-8°C

RID/ADR certification :

UN 3261 8 / PG 2

Alternative Distributors of [3-Bromopyruvic acid]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Downloads

Mol File:

-/-

MSDS:

-/-

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