8-Bromoadenosine 3',5'-cyclic Monophosphothioate, Sp-Isomer sodium salt | CAS 127634-20-2

Element: monophosphothioate bromoadenosine cyclic isomer sodium salt

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C-S » Chemicals » bromoadenosine-cyclic-monophosphothioate-isomer-sodium-salt-PX72269

Identification

8-Bromoadenosine 3',5'-cyclic Monophosphothioate, Sp-Isomer sodium salt

CAS:

127634-20-2

EINECS:

Molecular Formula:

C₁₀H₁₀BrN₅O₅PS.Na

MDL:

MFCD04037240

SMILES:

C1C2C(C(C(O2)N3C4=C(C(=NC=N4)N)N=C3Br)O)OP(=S)(O1)[O-].[Na+]

Synonym:

8-bromoadenosine-3'',5''-cyclic monophosphothioate sp isomer ; sp-8-br-camps sodium salt ; 8-bromoadenosine 3',5'-cyclic monophosphothioate, sp-isomer sodium salt ; sp-8-br-camps ; 8-bromoadenosine-3',5'-cyclic monophosphorothioate, sp-isomer sodium salt ; 8-bromoadenosine-3',5'-cyclic monophosphorothioate sodium salt, spisomer ; adenosine 3',5'-cyclic monophosphorothioate, 8-bromo-, sp-isomer, sodium salt ; sp-8-br-camps, na ; 8-br-camps na, sp-isomer ; 8-bromoadenosine 3',5'-cyclic monophosphothiaoate, sp-isomer sodium salt ; 8-bromoadenosine 3',5'-cyclic monophosphothioate,sp-lsomer sodium salt

Description

8-Bromoadenosine 3',5'-cyclic Monophosphothioate, Sp-Isomer sodium salt is a metabolically resistant activator of PKA (cAMP-dependent protein kinase) (cAMP agonist). No metabolic side effects as observed with dibutyryl-cAMP (N6,O2'-Dibutyryladenosine 3',5'-cyclic monophosphate) or 8-Br-cAMP (8-Bromoadenosine-3',5'-cyclic monophosphate). Significantly more lipophilic and membrane permeant as compared to Sp-cAMPS (Adenosine 3',5'-cyclic monophosphothioate, Sp isomer).

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Properties for 8-Bromoadenosine 3',5'-cyclic Monophosphothioate, Sp-Isomer sodium salt

Molecular Weight:

446.15 g·mol−1

Solubility:

Soluble in water, and aqueous buffer.

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