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3-Bromo-7-nitroindazole

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Formula: C7H4BrN3O2
CAS: 74209-34-0
search Element: nitroindazole bromo
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Identification

Structural Formula
3-Bromo-7-nitroindazole
CAS:
74209-34-0
EINECS:
Molecular Formula:
C7H4BrN3O2
MDL:
MFCD00159910
SMILES:
C1=CC2=C(NN=C2C(=C1)[N+](=O)[O-])Br
Synonym:


Description

3-Bromo-7-nitroindazole is a 7-nitro indazole derivative that inhibits bovine NOS3 and rat NOS1 enzyme activity. This compound was also reported to provide significant neuroprotection against ischaemia-induced brain damage in rat models. Experiments suggest that 3-Bromo-7-nitroindazole displays the capacity to prevent effects of MCPG, a metabotropic receptor antagonist. Metabotropic receptors decrease synaptic transmission in murine models.


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A.G. Scientific
AS6902070
Santa Cruz Biotechnology, Inc.
200347
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Prices & Availability




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Properties for 3-Bromo-7-nitroindazole

Molecular Weight:
242.03 g·mol−1
Density:
2.0 g/cm3
Melting point:
179-181° C
Boiling point:
248.88° C
Solubility:
Soluble in DMSO (50 mg/ml), DMF (~20 mg/ml), ethanol (~20 mg/ml), PBS (pH 7.2) (~50 µg/ml), 50:50 solution of DMSO:water (1 mg/ml), methanol, water containing 10% DMSO, dichloromethane, ethyl acetate, and water (< 50 µg/ml) at 25° C.
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Safety & Transport Information

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Alternative Distributors of [3-Bromo-7-nitroindazole]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Molekula GmbH | ABCR GmbH & Co. KG | Suzhou Rovathin Pharmatech Co., Ltd | Share Chemical Co., Ltd. | TRUST&WE Co., Ltd. | Jinan Great Chemical Co., Ltd. | East Chemical Industry Co., Ltd. | Jinan Haohua Industry Co., Ltd.

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